Vinca alkaloids

(redirected from Catharanthus alkaloids)
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Vinca alkaloids

Cytotoxic drugs used to prevent the replication of cells.
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Growth inhibition in HL60, K562 leukemia and EA.hy926 umbilical vein cells by Catharanthus alkaloids was detected by WST-1 and lactate dehydrogenase (LDH) assays.
These Catharanthus alkaloids are also used for the treatment of both malignant and nonmalignant diseases and in platelet and platelet associated disorders.
The Catharanthus alkaloids. Marcel Dekker, New York, NY., pp: 45-83.