cephalothin

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Related to Cefalotin: cephalothin, Keflin

cephalothin

(ˈsɛfələˌθɪn)
n
a cephalosporin antibiotic often used in the treatment of bacterial infections
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
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Noun1.cephalothin - a semisynthetic analogue of cephalosporin
cephalosporin, Mefoxin - one of several broad spectrum antibiotic substances obtained from fungi and related to penicillin (trade names Mefoxin); addition of side chains has produced semisynthetic antibiotics with greater antibacterial activity
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pneumoniae College Non-college College Non-college women women women women (n = 9) (n = 16) (n = 7) (n = 5) Amoxicillin 1 9 3 3 -clavulanate Cefuroxime - 5 - - Cefotaxime - 5 - - Ceftazidime - 5 - - Cefazolin 4 10 4 4 Cefoxitin - 6 2 3 Cefalotin 4 6 4 4 Ertapenem - 4 1 - Meropenem - 5 1 - Ciprofloxacin - 6 1 - Amikacin - 5 1 - Gentamicin - 7 - - ESBL (Ceftazidime - 1 - - /Ceftazidime -clavulanate) ESBL: Extended-spectrum [beta]-lactamases
The dog was hospitalized for three days to control post-surgical pain (morphine 0.5mg x [kg.sup.-1]SC, q12h; tramadol 2mg x [kg.sup.-1] and dipyrone 25mg x [kg.sup.-1] both SC, q8h; meloxicam 0.1mg x [kg.sup.-1]SC, q24h), antibiotic therapy (cefalotin 30mg x [kg.sup.-1]SC, q8h) and for thoracic drainage.
Glycine 3000 Vancomycin 1 80 (CH) Vancomycin 0.5 80 (CH) Cefalotin 4 Glycine 3000 Vancomycin 1 80 (A) Vancomycin 0.5 80 (A) Cefamandole 2 80 (A) Glycine 3000 Vancomycin 1 Campylobacter sp.
ATB AMP AMOX TIC PIP CEFA CEFO CEFTA ERTA Result R R R R R R R S ATB IMI AMI GENTA TOBRA Ac NA CIPRO OFLO NITRO Result S R R S R R R R AMP: ampicillin, AMOX: amoxicillin, TIC: ticarcillin, PIP: piperacillin, CEFA: cefalotin, CEFO: cefotaxime, CEFTA: ceftazidime, ERTA: ertapenem, IMI: imipenem, AMI: amikacin, GENTA: gentamicin, TOBRA: tobramycin, Ac NA: nalidixic acid, CPRO: ciprofloxacin, OFLO: ofloxacin, and NITRO: nitrofurantoin.
The antimicrobials tested were amikacin (30 [micro]g), amoxicillin (10 [micro]g), ampicillin (10 [micro]g), cefalotin (30 [micro]g), ciprofloxacin (5 [micro]g), clindamycin (2 [micro]g), chloramphenicol (30 [micro]g), erythromycin (10 [micro]g), gentamicin (10 [micro]g), nitrofurantoin (300 [micro]g), norfloxacin (10 [micro]g), penicillin G (10 [micro]g), tetracycline (30 [micro]g), and vancomycin (30 [micro]g).
strain showed resistance to the following: ampicillin (AMP), amoxicillin-clavulanate (AMC), cefalotin (CF), piperacillin (PIP), piperacillin-tazobactam (TZP), cefuroxime (CXM), cefoxitin (FOX), cefotaxime (CTX), ceftriaxone (CRO), aztreonam (ATM), ceftazidime (CAZ), cefepime (FEP), imipenem (IPM), meropenem (MEM), ertapenem (ETP), trimethoprim-sulphamethoxazole (SXT), amikacin (AK), tobramycin (NN), netilmicin (NET), ampicillin-sulbactam (SAM), ciprofloxacin (CIP), chloramphenicol (C).
To identify ESBL-producing strains, the cultures were screened with the following antibiotics: cefotaxime (CTX, 30 [micro]g), ceftazidime (CAZ, 30 [micro]g), cefetamet (CEF, 10 [micro]g), cefalotin, (CFL; 30 [micro]g), and aztreonam (ATM, 30 [micro]g), according to the CLSI guidelines (18).
coli in pneumonia patients was sensitive to imipenem (81.8%), gentamicin 8(72.7%), amoxycillin+clavulanate 4(36.4%), ciprofloxacin 3(27.3%), cefixime 2(18.2%), cotrimoxazole 2(18.2%), cefalotin 1(9.1%) and norfloxacin 1(9.1%).
aureus isolates were tested for susceptibility to penicillin (10 u/disk); imipenem (10 pg/disk); cefazoline (30 pg/disk); cefalotin (30 pg/disk); ceftriaxone (30 pg/disk); gentamicin (10 pg/disk); ciprofloxacin (5 pg/disk); clindamycin (2 pg/disk); azithromycin (15 pg/disk); erythromycin (15 pg/disk); mupirocin (30 pg/disk); rifampicin (5 pg/disk); tetracycline (30 pg/disk); trimethoprim (5 pg/disk); vancomycin (30 pg/disk) and nitrofurantoin (300 pg/disk) by the Kirby-Bauer disk diffusion method.
Resistance to cefalotin (62.1%), trimethoprim-sulfamethoxasole (43.1%), amoxycillin-clavulanate (34.8%), ampicillin (30.4%), cefixim (26.3%) and nitrofurantoin (3.6%) was found in E.