Patients were randomly divided into 2 groups regarding antibiotic prophylaxis: ceftriaxone or cefazoline
After microbiological sampling of the secretions in the wound, we started intravenous cefazoline
(1 g every 6 h) and washed the ulcer.
100 100 100 100 100 52 100 100 Enterobacter species 100 100 0 100 100 0 0 100 Fos: fosfomycin; Cefu: cefuroxime; Cf: cefazoline
; Cef: cefepime; Ceft: ceftriaxone; Am: ampicillin; Amo/clav: amoksisilin/clavulonic acid; Fm: nitrofurantoin Tablo 4.
Prior to the procedure, antibiotic prophylaxis (2g of cefazoline
) was administered intravenously.
Minimal inhibitory concentrations (MICs) of various antibiotics for Klebsiella pneumoniae isolate Antibiotic MIC (mg/L) Amoxycillin >128 Amoxycillin/clavulanate >128 Piperacillin >128 Piperacillin/tazobactam >128 Cefazoline
>128 Cefuroxime >128 Ceftazidime >128 Cefotaxime >128 Ceftriaxone >128 Cefepime >128 Ertapenem 16 Imipenem 2 Meropenem 2 Gentamicin >128 Ciprofloxacin 32 Colistin 0.032
Antimicrobial susceptibility was carried out by disc Diffusion method (modified Kirby-Bauer method) against the 12 most commonly prescribed antimicrobials in SSGH for Gram-positive organisms cefazoline
(CZ), chloramphenicol (C), ciprofloxacin (CIP), cloxacillin (CX), erythromycin (E), oxacillin (OX), penicillin (P), cefotaxime (CTX), roxithromycin (RXT), amoxycillin+clavulanic acid (AMC) and vancomycin and for Gram-negative organisms Ampicillin+sulbactam, gentamicin (G), CTX, Amikacin (AN), netilmicin (NET), CIP, imipenem (IPM), gatifloxacin (GF), ofloxacin (OFX), piperacillin (PIP), piperacillin+tazobactam (TZP), and tobramycin (TOB).
Current guidelines recommend the single intraoperative use of cefazoline
for gastric cancer surgery .
Loss to ceftazidime, then follow-up changed to gentamicin and ciprofloxacin (4) Cefazoline
, Healed in 6 weeks gentamicin with faint scar and no visual impairment (5) Cefazoline
, Healed completely in gentamicin 9 days
aureus strainsof human clinical infections had the highest resistance against penicillin (100%), cephalothin (100%), cefazoline
(100%), ceftireaxon (100%), azitromycin (62.12%), tetracycline (57.57%) and erythromycin (54.54%) which was similar to our findings.
Patient was treated with fortified cefazoline
5%, fortified tobramycin 1.3%, atropine eye drops 1%, oral vitamin c (500mg bid), oral antibiotic (ofloxacin 200mg bid) and tablet diamox 250mg tid.