amyotrophic lateral sclerosis

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Related to Charcot disease: Charcot triad

a·my·o·tro·phic lateral sclerosis

 (ā′mī-ə-trō′fĭk, -trŏf′ĭk, ā-mī′-)
n. Abbr. ALS
A chronic, progressive disease marked by gradual degeneration of the nerve cells in the spinal cord that control voluntary muscle movement, causing muscle weakness, atrophy, and eventual paralysis. Also called Lou Gehrig's disease.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

amyotrophic lateral sclerosis

(ˌæmɪəʊˈtrəʊfɪk)
n
(Pathology) a form of motor neurone disease in which degeneration of motor tracts in the spinal cord causes progressive muscular paralysis starting in the limbs. Also called: Lou Gehrig's disease
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

a•my•o•troph′ic lat′eral sclero′sis

(ˌeɪ maɪ əˈtrɒf ɪk, -ˈtroʊ fɪk, eɪˌmaɪ ə-)
n.
a nervous system disease in which degeneration of motor neurons in the brain stem and spinal cord leads to atrophy and paralysis of the voluntary muscles. Abbr.: ALS Also called Lou Gehrig's disease.
[1885–90; a-6 + myo- + -trophic]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.amyotrophic lateral sclerosis - thickening of tissue in the motor tracts of the lateral columns and anterior horns of the spinal cordamyotrophic lateral sclerosis - thickening of tissue in the motor tracts of the lateral columns and anterior horns of the spinal cord; results in progressive muscle atrophy that starts in the limbs
nervous disorder, neurological disease, neurological disorder - a disorder of the nervous system
induration, sclerosis - any pathological hardening or thickening of tissue
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
Clinical history of diabetes and Charcot disease was recorded by secondary diagnosis, glycated haemoglobin (HbA1c) levels, and basic patient characteristics.
Charcot disease of the foot is a well-described complication of diabetes mellitus and other neuropathic disease processes.
The 'Amrita Sling Technique', invented at AIMS, is a novel surgical technique to permanently stabilize the foot and ankle after conventional reconstruction of destroyed mid foot and hind foot bones, in case of 'Charcot disease'- usually seen as a result of autonomic neuropathy in diabetes mellitus and other neurological conditions.