Chelerythrine


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Chel`e`ryth´rine


n.1.(Chem.) An alkaloidal principle obtained from the celandine, and named from the red color of its salts. It is a colorless crystalline substance, and acts as an acrid narcotic poison. It is identical with sanguinarine.
References in periodicals archive ?
Sun, Structural modification of sanguinarine and chelerythrine and their antibacterial activity, Nat.
Potentiation of dopamine-induced currents in B8 by GABA and baclofen was blocked by the [GABA.sub.B] antagonist phaclofen, the non-specific G-protein inhibitor GDP[beta]3S, and the protein kinase C (PKC) inhibitor chelerythrine (Fig.
A second neuromodulator, chelerythrine chloride (CC) is a protein kinase C (PKC) blocker.
Abbreviations ARM: Armepavine BBM: Berbamine BBR: Berberine CHD: Chelidonine CHE: Chelerythrine CID: Collision-induced dissociation ISQA: Isoquinoline alkaloids JTR: Jatrorrhizine MGN: Magnoflorine MS: Mass spectrometry NMC: N-Methylcoclaurine OBB: Obaberine PLT: Palmatine STP: Stylopine TIC: Total ion current.
ochroleuca, and a great variety of alkaloids (berberine, palmatine, protopine, sarguinarine, optisine, chelerythrine, atropine, dihydrosanguinarine, dihydro-chelerythrine, [alpha]-allacriptopine, heleritrine, queilantifoline, scouletrine, reticuline, and copsitine) were identified (Israilov et al.
Yao, "Rapid determination of protopine, allocryptopine, sanguinarine and chelerythrine in fruits of Macleaya cordata by microwave-assisted solvent and HPLC-ESI/MS," Phytochemical Analysis, vol.
In first species secretory cells of laticifers containing alkaloids chelerythrine and sanguinarine have fluoresced in green-yellow, while second species enriched in anthraquinones have demonstrated the emission in orange-red.
In some experiments, inhibitors of NADPH oxidase, apocynin (150 or 300 [micro]M, Sigma-Aldrich) or VAS2870 (20 [micro]M, Sigma-Aldrich), or the protein kinase C inhibitors chelerythrine (10, 50, and 100 [micro]M, Sigma-Aldrich) or Go6983 (0.1, 1, 10 [micro]M, Sigma-Aldrich) were added to the cells 20 min before addition of the L-012 dye and stimulation with PDBu or LPS.
Niu, "Protective effect of chelerythrine against ethanol-induced gastric ulcer in mice," Chemico-Biological Interactions, vol.
Treatment with PKC inhibitor chelerythrine or BIM-1 abolished fibroblast growth factor-2 (FGF-2) mediated protection against DOX-induced apoptosis, suggesting that PKC activation is an important prosurvival mechanism downstream of FGF-2 [209].
The plant contains, as major constituents, isoquinoline alkaloids (such as sanguinarine, chelidonine, chelerythrine, berberine, protopine and coptisine), flavonoids, and phenolic acids.
In vitro antifungal activity of sanguinarine and chelerythrine derivatives against phytopathogenic fungi.