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A cartilage cell located in a lacuna of the cartilage matrix.
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These cells, known as chondrocytes, are returned into the patient's defect area in a second surgical procedure.
These adipocytes, osteoblasts and chondrocytes are distinct from another production line in the bone marrow--the hematopoietic system--that makes red blood cells, blood-clotting cells and cells of the immune system.
The Authors would like to correct Figure 6 and Figure 8 that were published incorrectly in the article "Effect of JJYMD-C, a novel synthetic derivative of gallic acid, on proliferation and phenotype maintenance in rabbit articular chondrocytes in vitro" in volume 47 no.
On the basis of morphology of chondrocytes and matrix, articular cartilage structure can be divided into three zones; superficial (tangential), middle (transitional) and deep zone.
Hyaline cartilage, such as that found in the nose, microscopically consists of chondrocytes. Derived from mesenchymal stem cells (MSCs), chondrocytes are responsible for producing the extracellular matrix that mainly consists of Type II collagen and proteoglycans.
Linear growth or longitudinal growth achieved in human life, is determined by a process of differentiation, proliferation and maturation of the chondrocytes in the growth plate.
A smooth connective tissue that protects the joints, cartilage is produced by cells called chondrocytes but is not easily replaced once it is damaged.
Mechanical stimulation has been shown to have a strong influence on chondrocyte biosynthetic activity.[2] Furthermore, multiple studies have suggested a regulatory role for intracellular Ca2+ in endochondral ossification, a process that includes chondrocyte proliferation, differentiation, and apoptosis.[3] Based on the above findings, we hypothesized that mechanical stress alone or in combination with the voltage-sensitive Ca2+ channel inhibitor verapamil would stimulate chondrocytes with respect to AGC biosynthesis.
14/782,070 related to methods of producing pluripotent stem cell-derived chondrocytes, chondrocyte lineage cells, cartilage-like tissue and cartilage.
The severity of the osteoarthritic lesions was graded on a scale of 0-14 by three independent observers using the Mankin scoring system as follows: Mankin score 0, normal cartilage with a smooth surface and a regular zonal distribution of chondrocytes; Mankin score 1-4, cartilage surface shows fibrillations and a superficial loss of proteoglycans, but the zonal structure is intact; Mankin score 5-8, cartilage samples have clefts reaching down to the middle cartilage zone, and clusters of proliferating chondrocytes are present; and Mankin score [greater than or equal to] 9, severely affected cartilage samples with clefts reaching down to the deep zone, in which the tangential zone is lost and chondrocyte clusters are present.
Articular cartilage is a thin connective tissue, lining the ends of long bones, and consisting of predominantly water, aggrecan, colla gen type II, and chondrocytes (Almarza and Athanasiou, 2004; Browne and Branch, 2000).