Hand-Schuller-Christian disease

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Noun1.Hand-Schuller-Christian disease - inflammatory histiocytosis associated with disturbance of cholesterol metabolism; occurs chiefly in young children and is characterized by cystic defects of the skull and diabetes insipidus
histiocytosis - a blood disease characterized by an abnormal multiplication of macrophages
References in periodicals archive ?
Hand Schuller Christian disease is a rare entity comprising of exophthalmos, diabetes insipidus and geographical map skull.
There is hardly any doubt in my mind that, since modernity is simply a Christian heresy, nothing is better qualified to cure a Christian disease than Christianity itself.
In the past, LCH was subdivided into three categories: Letterer-Siwe disease (acute disseminated disease), Hand-Schuller Christian disease (multifocal or uni-focal disease), and Eosinophilic granuloma (usually uni-focal disease) (Table).

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