prophase

(redirected from Chromatin condensation)
Also found in: Thesaurus, Medical, Encyclopedia.
Related to Chromatin condensation: prophase

pro·phase

 (prō′fāz′)
n.
1. The first stage of mitosis, during which the chromosomes condense and become visible, the nuclear membrane breaks down, and the spindle apparatus forms at opposite poles of the cell.
2. The first stage of meiosis, constituted by a series of events that include the thickening and coiling of the chromosomes, synapsis of homologous chromosomes, tetrad formation, and crossing over.

pro·pha′sic (-fā′zĭk) adj.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

prophase

(ˈprəʊˌfeɪz)
n
1. (Biology) the first stage of mitosis, during which the nuclear membrane disappears and the nuclear material resolves itself into chromosomes. See also metaphase, anaphase, telophase
2. (Biology) the first stage of meiosis, divided into leptotene, zygotene, pachytene, diplotene, and diakinesis phases
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

pro•phase

(ˈproʊˌfeɪz)

n.
the first stage of mitosis or meiosis in cell division, during which the nuclear envelope breaks down and strands of chromatin form into chromosomes.
[1880–85]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.

pro·phase

(prō′fāz′)
The first stage of cell division. Before prophase begins, the chromosomes duplicate to form two long, thin strands called chromatids. During prophase itself, the chromatids condense and thicken and the membrane surrounding the nucleus disappears. In mitosis, prophase is followed by metaphase. See more at meiosis, mitosis.
The American Heritage® Student Science Dictionary, Second Edition. Copyright © 2014 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.prophase - the first stage of meiosisprophase - the first stage of meiosis    
diakinesis - the final stage of the prophase of meiosis
diplotene - the fourth stage of the prophase of meiosis
leptotene - the first stage of the prophase of meiosis
meiosis, miosis, reduction division - (genetics) cell division that produces reproductive cells in sexually reproducing organisms; the nucleus divides into four nuclei each containing half the chromosome number (leading to gametes in animals and spores in plants)
pachytene - the third stage of the prophase of meiosis
phase of cell division - a stage in meiosis or mitosis
synezesis, synizesis - the contraction of chromatin towards one side of the nucleus during the prophase of meiosis
zygotene - the second stage of the prophase of meiosis
2.prophase - the first stage of mitosis
mitosis - cell division in which the nucleus divides into nuclei containing the same number of chromosomes
phase of cell division - a stage in meiosis or mitosis
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
Translations
profaza

pro·phase

n. profase, primera fase en la mitosis celular.
English-Spanish Medical Dictionary © Farlex 2012
References in periodicals archive ?
Although the results of AB staining have shown a clear relationship between abnormal sperm chromatin condensation and male infertility (34), the correlation between the percentage of AB staining reacted spermatozoa and other sperm parameters remains controversial (35-37).
The chromatin condensation against the nuclear envelope, cell shrinkage, surface blebbing and generation of apoptotic bodies by cell fragmentation were evidence of apoptosis.
Early apoptotic cells stain green and contain bright green dots in the nuclei as a consequence of chromatin condensation and nuclear fragmentation.
Although the electron microscopy did not reveal a constant chromatin condensation and nuclear fragmentation (cell death), the cardiomyocyte is deteriorated (Communal et al.
Chromatin condensation and fragmentation are two major indicators of cell apoptosis.
Diploidy has been related with an increase of sperm head area and alteration in chromatin condensation in bulls [41], although in stallion sperm, nuclear area was similar between haploid and diploid sperm, but a significant difference was observed among these two subpopulations and polyploid sperm [45].
(B) illustrates chromatin condensation and fragmentation (arrows), (B)(i) untreated (4000x), (B)(ii) 10 [micro]M Cisplatin treated cells for 4h (5000x), (B)(iii) 20 [micro]M Carboplatin treated cells for 2h (12000x), and (B)(iv) 20 [micro]M Oxaliplatin treated cell for 2 h (5000x).
The level of chromatin condensation was measured using the Hoechst, YO-PRO1, and propidium iodide (PI) stains from the Chromatin Condensation & Membrane Permeability Dead Cell Apoptosis Kit (Life Technologies), similarly to the method reported by Muders et al.
Results of the present study indicated that EVO reduced the viability of different types of human ovarian cancer cells including A2780, A2780CP, SKOV-3, and ES-2 cells according to the occurrence of apoptotic characteristics such as DNA ladders, chromatin condensation, and caspase-3 and PARP protein cleavage.
Apoptosis displays morphological and biochemical hallmarks [4, 5] involving chromatin condensation, nuclear fragmentation, rounding-up of the cell, reduction of cellular volume, and metabolic and energetic modifications of the mitochondria.
Sperm chromatin condensation is another valuable index of sperm quality that is essential for the capacity of the sperm to fertilize the ovum [19].