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Related to Chromosomal non-disjunction: Meiotic nondisjunction


The failure of paired chromosomes or sister chromatids to separate and go to different cells during meiosis.

non′dis·junc′tion·al adj.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Genetics) the failure of paired homologous chromosomes to move to opposite poles of the cell during meiosis
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
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Noun1.nondisjunction - meiosis in which there is a failure of paired homologous chromosomes to separate; results in an abnormal number of chromosomes in the daughter cells
meiosis, miosis, reduction division - (genetics) cell division that produces reproductive cells in sexually reproducing organisms; the nucleus divides into four nuclei each containing half the chromosome number (leading to gametes in animals and spores in plants)
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References in periodicals archive ?
The criteria for inclusion of subjects was normal stature, no genetic abnormality, no chromosomal non-disjunction cases, no cases of dwarfism or gigantism, no history of breast cancer and no history of isolated growth hormone deficiency up to two previous generations in the family respectively.
The chromosomal non-disjunction was the most common type of chromosomal abnormality in Down syndrome.
Investigations on Drosophila melanogaster indicated developed abnormalities due to the effect of mutagenic factors on meiotic chromosomal non-disjunction (Ramel, 2003).