nondisjunction

(redirected from Chromosomal non-disjunction)
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Related to Chromosomal non-disjunction: Meiotic nondisjunction

non·dis·junc·tion

 (nŏn′dĭs-jŭngk′shən)
n.
The failure of paired chromosomes or sister chromatids to separate and go to different cells during meiosis.

non′dis·junc′tion·al adj.

nondisjunction

(ˌnɒndɪsˈdʒʌŋkʃən)
n
(Genetics) the failure of paired homologous chromosomes to move to opposite poles of the cell during meiosis
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.nondisjunction - meiosis in which there is a failure of paired homologous chromosomes to separate; results in an abnormal number of chromosomes in the daughter cells
meiosis, miosis, reduction division - (genetics) cell division that produces reproductive cells in sexually reproducing organisms; the nucleus divides into four nuclei each containing half the chromosome number (leading to gametes in animals and spores in plants)
References in periodicals archive ?
Investigations on Drosophila melanogaster indicated developed abnormalities due to the effect of mutagenic factors on meiotic chromosomal non-disjunction (Ramel, 2003).
It has recently been shown that chromosomal non-disjunction occurs with a higher frequency in binucleated cells that fail to complete cytokinesis, rather than in cells that have completed cytokinesis [48].
Aneuploidy arising from chromosomal non-disjunction (NDJ) is particularly problematic for students, since it arises in the context of meiosis, itself a challenging subject.