nondisjunction

(redirected from Chromosomal nondisjunction)
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Related to Chromosomal nondisjunction: Meiotic nondisjunction

non·dis·junc·tion

 (nŏn′dĭs-jŭngk′shən)
n.
The failure of paired chromosomes or sister chromatids to separate and go to different cells during meiosis.

non′dis·junc′tion·al adj.

nondisjunction

(ˌnɒndɪsˈdʒʌŋkʃən)
n
(Genetics) the failure of paired homologous chromosomes to move to opposite poles of the cell during meiosis
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.nondisjunction - meiosis in which there is a failure of paired homologous chromosomes to separate; results in an abnormal number of chromosomes in the daughter cells
meiosis, miosis, reduction division - (genetics) cell division that produces reproductive cells in sexually reproducing organisms; the nucleus divides into four nuclei each containing half the chromosome number (leading to gametes in animals and spores in plants)
References in periodicals archive ?
On the other hand, it has been postulated that chemicals inducing crosslinks increase the probability of chromosomal nondisjunction (7,17).
has been postulated that chemicals inducing crosslinks (DNA:DNA and/or DNA:protein) increase the probability of chromosomal nondisjunction, possibly through disturbances in recombination or kinetochore and microtubule perturbations during cell division (7,17).
1995), such centromeric incompatibilities may be produced by mechanical pairing deficiencies leading to chromosomal nondisjunction (Redi and Capanna 1988).