nondisjunction

(redirected from Chromosomal nondisjunction)
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Related to Chromosomal nondisjunction: Meiotic nondisjunction

non·dis·junc·tion

 (nŏn′dĭs-jŭngk′shən)
n.
The failure of paired chromosomes or sister chromatids to separate and go to different cells during meiosis.

non′dis·junc′tion·al adj.

nondisjunction

(ˌnɒndɪsˈdʒʌŋkʃən)
n
(Genetics) the failure of paired homologous chromosomes to move to opposite poles of the cell during meiosis
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.nondisjunction - meiosis in which there is a failure of paired homologous chromosomes to separate; results in an abnormal number of chromosomes in the daughter cells
meiosis, miosis, reduction division - (genetics) cell division that produces reproductive cells in sexually reproducing organisms; the nucleus divides into four nuclei each containing half the chromosome number (leading to gametes in animals and spores in plants)
References in periodicals archive ?
On the other hand, it has been postulated that chemicals inducing crosslinks increase the probability of chromosomal nondisjunction (7,17).
has been postulated that chemicals inducing crosslinks (DNA:DNA and/or DNA:protein) increase the probability of chromosomal nondisjunction, possibly through disturbances in recombination or kinetochore and microtubule perturbations during cell division (7,17).