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Related to ciclosporin: tacrolimus


Variant of cyclosporine.


(ˌsaɪkləʊˈspɔːrɪn) or


(Pharmacology) a drug extracted from a fungus and used after organ transplantation to suppress the body's immune mechanisms, and so prevent rejection of an organ
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Treatment involves the use of ciclosporin drops (which are often required lifelong) and, initially at least, artificial tear replacements and antibiotics.
Another study suggested that for effective immunosuppressive treatment in dogs, the dosage of ciclosporin A requires adjustments in the course of therapy, guided by serum values and the animals age (MORINI et al.
Treatment options include corticosteroids and ciclosporin as first line agents.
Ciclosporin administration during pregnancy induces ultrastructural changes on pancreatic beta-cells of newborn rats.
All of the drugs are treatment options for children and young people, according to their age, whose psoriasis is severe and has not improved with other treatments, such as ciclosporin, methotrexate or phototherapy, or in instances where these can't be used.
Patients with mild disease usually require only topical treatment however those with moderate to severe disease generally require phototherapy, ciclosporin, methotrexate and acitretin.
Ciclosporin A proof of concept study in patients with active, progressive HTLV-1 associated myelopathy/tropical spastic paraparesis.
48,49) Ciclosporin was licensed in the UK in 2015 (Ikervis).
Ciclosporin population pharmacokinetics and Bayesian estimation in thoracic transplant recipients.
Open trial of ciclosporin treatment for Stevens- Johnson syndrome and toxic epidermal necrolysis.
In my 10 years dialysing at home a new drug called ciclosporin was discovered and I believe this has helped my kidney survive along with the good care of local doctors and the renal team at James Cook University Hospital, Dr Kenward, Dr Patterson and now Dr Wroe.