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He was given imipenem and cilastatin sodium, vancomycin, and caspofungin with reduced dose of corticosteroid.
They tested 12 of the most common types of antibiotics, finding that two combinations in particular - piperacillin and tazobactam, and imipenem and cilastatin - led to a higher risk of a life-threatening inflammatory condition called graft-versus-host disease (GVHD).
Comparison of efficacy of cefoperazone/sulbactam and imipenem/ cilastatin for treatment of Acinetobacter bacteremia.
Eight hours after sepsis induction, when the animals showed clinical signals of sepsis (ruffled fur, hypothermia, lacrimation, lethargy), a combination of the antibiotics imipenem and cilastatin (8 mg/kg) was injected subcutaneously to increase the survival rate.
4 mg/kg at 12 and 24 h and then daily) along with intravenous injectible Imipenem and Cilastatin combination (500 mg plus 500 mg) every six hourly through peripheral intravenous line which were given for five continuous days.
The drug discs used were as follows: Penicillin Group: Methicillin (Oxacillin 5ug), Amoxicillin (20ug), Amoxicillin + Clavulanic acid (20/10ug), Piperacillin + Tazobactam (100/10 ug ) , Glycopeptides: Vancomycin (30ug), Teicoplanin (30ug), Carbapenems: Meropenem (10ug), Imipenem + Cilastatin Sodium (10 ug), Cephalosporins: Cephradine (25ug), Ceftriaxone (30ug), Ceftazidime (30 ug), Cefoperazone (75ug) and Fluoroquinolones: Ciprofloxacin (5ug) and Enoxacin (10ug).
The firm also launched nine new products last year, including Valaciclovir and Imipenem + Cilastatin.
M2 PHARMA-February 8, 2012-APP Pharmaceuticals to launch Imipenem and Cilastatin for Injection, USP and Meropenum for Injection, USP in the US.
Cilastatin, given to extend the duration of imipenem, is also eliminated by the kidney.
Randomized trial of imipenem/ cilastatin versus gentamicin and clindamycin in mixed flora infections.
Active ingredient: imipenem / cilastatin (doe) amount of active substance: 500 mg / 500 mg pharmaceutical form: vial packaging conditions: unit dose maximum unit price: eur 2.
linezolid + imipenem and cilastatin sodium + voriconazole + oseltamivir phosphate) were regularly administered to the patients.
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