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n. pl. clos·trid·i·a (-ē-ə)
Any of various rod-shaped, spore-forming, chiefly anaerobic bacteria of the genus Clostridium, such as certain nitrogen-fixing species found in soil and those causing botulism and tetanus.

[New Latin Clōstridium, genus name, from Greek klōstēr, klōstr-, spindle, from klōthein, to spin.]

clos·trid′i·al (-əl) adj.


n, pl -iums or -ia (-ɪə)
(Microbiology) any anaerobic typically rod-shaped bacterium of the genus Clostridium, occurring mainly in soil, but also in the intestines of humans and animals: family Bacillaceae. The genus includes the species causing botulism and tetanus
[C20: from New Latin, literally: small spindle, from Greek klōstēr spindle, from klōthein to spin; see -ium]
closˈtridial, closˈtridian adj


(klɒˈstrɪd i əm)

n., pl. clos•trid•i•a (klɒˈstrɪd i ə)
any of several rod-shaped, spore-forming, anaerobic bacteria of the genus Clostridium, found in soil and in the intestinal tract.
[< New Latin (1880) < Greek klōstr-, <klōstḗr spindle]
clos•trid′i•al, clos•trid′i•an, adj.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.clostridium - spindle-shaped bacterial cell especially one swollen at the center by an endospore
eubacteria, eubacterium, true bacteria - a large group of bacteria having rigid cell walls; motile types have flagella
genus Clostridium - anaerobic or micro-aerophilic rod-shaped or spindle-shaped saprophytes; nearly cosmopolitan in soil, animal intestines, and dung
References in periodicals archive ?
Collagenase clostridium histolyticum (Xiaflex[R]) was approved on December 6, 2013, by the United States Food and Drug Administration (FDA) for use with patients with Peyronie's disease.
M2 EQUITYBITES-November 21, 2016-BioSpecifics Technologies reveals positive results from phase 2b study of collagenase clostridium histolyticum
M2 PHARMA-November 21, 2016-BioSpecifics Technologies reveals positive results from phase 2b study of collagenase clostridium histolyticum
2012a), and the temporal and spatial distributions of Bacillus and Clostridium histolyticum were determined by fluorescent in situ hybridization in their studies (Yi et al.
This enzyme, called collagenase, dissolves collagen and is harvested from a bacterium, clostridium histolyticum.
In analysing the gut microbiota, a significantly lower proportion of Clostridium histolyticum bacteria were observed in the probiotic group compared to placebo and prebiotics groups.
Xiapex - collagenase clostridium histolyticum - offers an alternative treatment option to surgery for the condition and can be administered by a trained physician.
You can have surgery or radiation, and a treatment is available called collagenase clostridium histolyticum that is injected.
Collagenase Clostridium histolyticum (Xiaflex; B) is given intramuscularly for the treatment of Dupuytren's contracture with a palpable cord.
First author Tatiana Demidova-Rice said, "We found that collagenase enzyme derived from Clostridium histolyticum bacteria releases biologically active fragments - peptides - from extracellular mammalian proteins.
Among specific topics are anti-glaucoma carbonic anhydrase inhibitors as opthalmologic drugs, crystallographic studies of carbonic anydrases from fungal pathogens for structure-assisted drug development, sulfonylated matrix metalloproteinase inhibitors, Clostridium histolyticum collagenase inhibitors in the drug design, angiotensin converting enzyme inhibitors, and inhibitors of histidinol dehydrogenases as antibacterial agents.
The product, collagenase Clostridium histolyticum, was approved specifically for adults with Dupuytren's contracture with a palpable cord, and will be marketed as Xiaflex by Auxilium Pharmaceuticals Inc.

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