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n. pl. clos·trid·i·a (-ē-ə)
Any of various rod-shaped, spore-forming, chiefly anaerobic bacteria of the genus Clostridium, such as certain nitrogen-fixing species found in soil and those causing botulism and tetanus.

[New Latin Clōstridium, genus name, from Greek klōstēr, klōstr-, spindle, from klōthein, to spin.]

clos·trid′i·al (-əl) adj.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


n, pl -iums or -ia (-ɪə)
(Microbiology) any anaerobic typically rod-shaped bacterium of the genus Clostridium, occurring mainly in soil, but also in the intestines of humans and animals: family Bacillaceae. The genus includes the species causing botulism and tetanus
[C20: from New Latin, literally: small spindle, from Greek klōstēr spindle, from klōthein to spin; see -ium]
closˈtridial, closˈtridian adj
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(klɒˈstrɪd i əm)

n., pl. clos•trid•i•a (klɒˈstrɪd i ə)
any of several rod-shaped, spore-forming, anaerobic bacteria of the genus Clostridium, found in soil and in the intestinal tract.
[< New Latin (1880) < Greek klōstr-, <klōstḗr spindle]
clos•trid′i•al, clos•trid′i•an, adj.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.clostridium - spindle-shaped bacterial cell especially one swollen at the center by an endospore
eubacteria, eubacterium, true bacteria - a large group of bacteria having rigid cell walls; motile types have flagella
genus Clostridium - anaerobic or micro-aerophilic rod-shaped or spindle-shaped saprophytes; nearly cosmopolitan in soil, animal intestines, and dung
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
Phase 2 Clinical Trial of Uterine Fibroids Future Development Plans Underway: BioSpecifics and its clinical partners continue to analyze the full Phase 1 data to guide the design of a Phase 2 study of collagenase clostridium histolyticum (CCH) for the treatment of uterine fibroids.
Endo International announced that clinical data from a Phase 3 investigational study of collagenase clostridium histolyticum for the treatment of cellulite will be presented by Lawrence Bass.
Collagenase Clostridium histolyticum (CCH) is the first licensed drug for the treatment of Peyronie's diease and is indicated in patients with palpable plaque and a curvature deformity of [greater than or equal to]30[degrees].
Collagenase clostridium histolyticum (Xiaflex[R]) was approved on December 6, 2013, by the United States Food and Drug Administration (FDA) for use with patients with Peyronie's disease.
We previously demonstrated that the subcutaneous injection of a recombinant protein consisting of the polycystic kidney disease (PKD) and Clostridium histolyticum collagenase collagen-binding domains (CBD) fused to basic fibroblast growth factor (bFGF; bFGF-PKDCBD) had greater skin fibroblast growth-promoting effects in nude mice than native bFGF [27].
Trial patients receiving collagenase clostridium histolyticum indicated statistically significant levels of improvement in the appearance of cellulite with treatment, as measured by the trial's primary endpoint (p
Swedish Orphan Biovitrum AB (publ) (Sobi) has received approval from Swissmedic, the Swiss Agency for Therapeutic Products, for Xiapex (collagenase clostridium histolyticum) for the treatment of adult men with Peyronie's disease.
Polymerase chain reaction (PCR) denaturing gradient gel electrophoresis combined with restriction fragment polymorphism (-RFLP) was used to analyze the diversity of the Bacillus community and its temporal-spatial distribution during swine manure composting (Yi et al., 2012a), and the temporal and spatial distributions of Bacillus and Clostridium histolyticum were determined by fluorescent in situ hybridization in their studies (Yi et al., 2012b).
This enzyme, called collagenase, dissolves collagen and is harvested from a bacterium, clostridium histolyticum. Its commercial name is Xiapex.
In analysing the gut microbiota, a significantly lower proportion of Clostridium histolyticum bacteria were observed in the probiotic group compared to placebo and prebiotics groups.

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