clotting factor

(redirected from Clotting factors)
Also found in: Thesaurus, Medical, Legal, Encyclopedia.

clotting factor

n
(Biochemistry) any one of a group of substances, including factor VIII, the presence of which in the blood is essential for blood clotting to occur. Also called: coagulation factor
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.clotting factor - any of the factors in the blood whose actions are essential for blood coagulation
plasma protein - any of the proteins in blood plasma
factor I, fibrinogen - a protein present in blood plasma; converts to fibrin when blood clots
factor II, prothrombin - a protein in blood plasma that is the inactive precursor of thrombin
factor III, thrombokinase, thromboplastin - an enzyme liberated from blood platelets that converts prothrombin into thrombin as blood starts to clot
calcium ion, factor IV - ion of calcium; a factor in the clotting of blood
cothromboplastin, factor VII, proconvertin, stable factor - a coagulation factor formed in the kidney under the influence of vitamin K
antihaemophilic factor, antihaemophilic globulin, antihemophilic factor, antihemophilic globulin, factor VIII, Hemofil - a coagulation factor (trade name Hemofil) whose absence is associated with hemophilia A
Christmas factor, factor IX - coagulation factor whose absence is associated with hemophilia B
factor X, prothrombinase - coagulation factor that is converted to an enzyme that converts prothrombin to thrombin in a reaction that depends on calcium ions and other coagulation factors
factor XI, plasma thromboplastin antecedent - coagulation factor whose deficiency results in a hemorrhagic tendency
factor XII, Hageman factor - coagulation factor whose deficiency results in prolongation of clotting time of venous blood
factor XIII, fibrinase - in the clotting of blood thrombin catalyzes factor XIII into its active form (fibrinase) which causes fibrin to form a stable clot
References in periodicals archive ?
If you bleed while taking warfarin, the drug's effects can be reversed with a drug called phytonadione (a synthetic form of vitamin K), or with fresh frozen plasma (FFP), which contains clotting factors.
Contract award notice: delivery of clotting factors and drugs on the list for reimbursement of the nhif.
USPRwire, Fri Nov 13 2015] Hemophilia is a rare bleeding disorder caused by deficiency of clotting factors such as VIII and IX.
The goal of treatment in patients with hereditary factor X deficiency is to replace their missing factor X without adding other clotting factors the patients do not need.
A: Hemophilia is a bleeding disorder in which blood has insufficient amount of certain proteins called blood clotting factors that are needed for blood clotting or coagulation, i.
Sergey Filipenko complained about lack of blood clotting factors purchased for people with hemophilia.
Most of the boys in this study were treated with prophylactic infusions of clotting factors, and tailoring treatment protocols to sports timetables might protect them further.
Basically, aPTT is affected by the activities of clotting factors XII, XI, X, IX, VIII, V, II, and I, as well as by high molecular weight kininogen and prekallikrein.
If you take clotting factors off the membrane, they're thousands of times less active.
Infusing a crystalloid solution (normal saline or lactated Ringer's solution) or stored packed red blood cells without clotting factors into a hemorrhaging patient will dilute the clotting factors and can actually make the patient more coagulopathic.
When blood vessels are injured, clotting factors help the platelets stick together to plug cuts and breaks at the site of the injury to stop the bleeding," Taher explained.
These ingredients or clotting factors allow platelet adhesion to occur.