clotting factor

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clotting factor

n
(Biochemistry) any one of a group of substances, including factor VIII, the presence of which in the blood is essential for blood clotting to occur. Also called: coagulation factor
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.clotting factor - any of the factors in the blood whose actions are essential for blood coagulation
plasma protein - any of the proteins in blood plasma
factor I, fibrinogen - a protein present in blood plasma; converts to fibrin when blood clots
factor II, prothrombin - a protein in blood plasma that is the inactive precursor of thrombin
factor III, thrombokinase, thromboplastin - an enzyme liberated from blood platelets that converts prothrombin into thrombin as blood starts to clot
calcium ion, factor IV - ion of calcium; a factor in the clotting of blood
cothromboplastin, factor VII, proconvertin, stable factor - a coagulation factor formed in the kidney under the influence of vitamin K
antihaemophilic factor, antihaemophilic globulin, antihemophilic factor, antihemophilic globulin, factor VIII, Hemofil - a coagulation factor (trade name Hemofil) whose absence is associated with hemophilia A
Christmas factor, factor IX - coagulation factor whose absence is associated with hemophilia B
factor X, prothrombinase - coagulation factor that is converted to an enzyme that converts prothrombin to thrombin in a reaction that depends on calcium ions and other coagulation factors
factor XI, plasma thromboplastin antecedent - coagulation factor whose deficiency results in a hemorrhagic tendency
factor XII, Hageman factor - coagulation factor whose deficiency results in prolongation of clotting time of venous blood
factor XIII, fibrinase - in the clotting of blood thrombin catalyzes factor XIII into its active form (fibrinase) which causes fibrin to form a stable clot
References in periodicals archive ?
Summary: Clotting factors are proteins that play an important role in blood clotting.
Wild-type mice and knockout disease models were dosed with human cells genetically engineered to produce stable blood plasma levels of the clotting factors missing in patients with hemophilia.
"Individuals with haemophilia have a fault in a gene that regulates the body's production of proteins called clotting factors. This can cause spontaneous bleeding as well as severe bleeding following injury or surgery.
Warfarin Interactions Warfarin blocks the action of vitamin K, which the liver uses to make clotting factors. "The drug is effective, but it has numerous interactions with food," Dr.
The body uses this to make clotting factors in the blood.
Request Brochure of this Report- https://www.factmr.com/connectus/sample?flag=B&rep_id=1093 Cryoprecipitated Antihemophilic Factor is a portion of plasma rich in clotting factors including fibrinogen and factor VII.
He added that although the disease cannot be fully cured, effective treatments such as Replacement Therapy, where clotting factors are dripped or injected into a vein, can go a long way in suppressing the ailment.
Abdelbari, there are two types of treatment regimens offered to patients with hemophilia at HMC, including on-demand therapy given to control sudden bleeding into the joint or muscle and the routine administration of clotting factors two to three times a week to prevent bleeding, known as prophylaxis.
According to (https://www.mayoclinic.org/diseases-conditions/hemophilia/symptoms-causes/syc-20373327) Mayo Clinic , "Hemophilia is a rare disorder in which your blood doesn't clot normally because it lacks sufficient blood-clotting proteins (clotting factors).
In the US and Europe, Shire's Hemlibra is approved as a treatment for patients who have developed resistance, or inhibitors, to standard treatments that include infusions of clotting factors that help stop bleeding in sufferers of haemophilia A.
Dr Ibrahim Mustafa, assistant professor of haematology at QU College of Health Sciences, noted that haemophilia is an inherited blood disorder which exhibits bleeding problem due to the lack of some clotting factors in patients' blood.