(redirected from Cofactors)
Also found in: Thesaurus, Medical, Encyclopedia.


1. One of two or more contributing factors.
2. A substance, such as a metallic ion or coenzyme, that must be associated with an enzyme for the enzyme to function.


1. (Mathematics) maths a number associated with an element in a square matrix, equal to the determinant of the matrix formed by removing the row and column in which the element appears from the given determinant. See minor
2. (Biochemistry) biochem a nonprotein substance that forms a complex with certain enzymes and is essential for their activity. It may be a metal ion or a coenzyme


(ˈkoʊˌfæk tər)

1. a contributing factor.
2. any of various organic or inorganic substances necessary to the function of an enzyme.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.cofactor - a substance (as a coenzyme) that must join with another to produce a given result
chemical compound, compound - (chemistry) a substance formed by chemical union of two or more elements or ingredients in definite proportion by weight
References in periodicals archive ?
An established biological route to generate nitrogen gas is via anammox bacteria, which use enzymes employing iron-based cofactors to combine nitrates and ammonia, yielding nitrogen gas and water.
Hydrogen borrowing requires mutually compatible cofactors shared by two enzymes and in some cases will require redesign of cofactor specificity.
Furthermore, EBV's cofactors have not been shown to parallel the geographic distribution of NPC.
12] and folic acid play a part in many vital bodily reactions, and function primarily as cofactors.
Nitrate reductase requires cofactors to function, which leads us to three important interactions.
In order for these reactions to occur suitably, the enzymes and cofactors that regulate their flow must be present in the proper balance.
Sulfite oxidase has cofactors of molybdenum, pyridoxine, cobalamine, and other influences.
ay-z] with cofactors z - x and d + by + (c + a)z if a + c [not equal to] 0, or a + c = 0 and b [not equal to] 0.
The Vitamin D Council points out that to receive the greatest benefit from increased levels of vitamin D, "the proper cofactors must be present in the body.
In humans, it has been suggested that human papillomaviruses--along with ultraviolet light--may act as cofactors in human skin cancer.
He covers metabolism overall and its context; enzymes and coenzymes; the transport of small molecules; glycolysis and fermentation; respiration; non-glycolytic routes; amino acids, pyrimidines, and purines; carbohydrates, cofactors, and inorganic constituents; lipids; catabolism; and stress.