collagenase

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col·lag·e·nase

 (kə-lăj′ə-nās′, -nāz′, kŏl′ə-jə-)
n.
Any of various enzymes that catalyze the hydrolysis of collagen and gelatin.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

collagenase

(ˈkɒlədʒəˌneɪz)
n
(Biochemistry) an enzyme that decomposes collagen
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.collagenase - any enzyme that catalyzes the hydrolysis of collagen and gelatin
enzyme - any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
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Additionally, possible excessive collagenolysis [11] near the cervix and lower uterine segment induced by misoprostol induction may result in undue fragility of tissues in this area and may interfere with effective retraction required for arrest of bleeding after labor.
Another important profibrotic factor produced mainly by platelets is that PAI-1 inhibits fibrinolysis, causing fibrin to remain at the site, triggering recruitment of inflammatory cells and subsequent release of profibrotic factors (cytokines, etc.); it also hinders collagenolysis and inhibits MMPs [39,40].
Non-steroidal anti-inflammatory drugs (NSAIDs) impairs collagenolysis. Other studies noted that NSAIDs have favourable impact on anastomotic healing by increasing the collagen production.
Multifocal areas of collagenolysis and eosinophilic infiltration were also seen.
The areca nut generates free radicals and causes local immunosuppression along with decreased collagenolysis capability of the mucosa.
CypA, as an MMP activator, initiates aortic aneurysm formation.[sup][21] The contribution of MMP to increased collagenolysis may be related to genetic polymorphisms present at a higher frequency in women with PFD.
Differential regulation of membrane type 1-matrix metalloproteinase activity by ERK 1/2- and p38 MAPK-modulated tissue inhibitor of metalloproteinases 2 expression controls transforming growth factor-[beta]1-induced pericellular collagenolysis. J Biol Chem.