complement fixation test

(redirected from Complement-fixation)
Also found in: Thesaurus.

complement fixation test

n
(Medicine) med a serological test for detecting the presence of a specific antibody or antigen, used in the diagnosis of syphilis, etc
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.complement fixation test - a blood test in which a sample of serum is exposed to a particular antigen and complement in order to determine whether or not antibodies to that particular antigen are present; used as a diagnostic test
Wasserman reaction, Wassermann test, Wassermann - a blood test to detect syphilis; a complement fixation test is used to detect antibodies to the syphilis organism treponema; a positive reaction indicates the presence of antibodies and therefore syphilis infection
blood test - a serologic analysis of a sample of blood
References in periodicals archive ?
Histoplasma complement-fixation antibody titers for both yeast and mycelial antigens were negative, but immunodiffusion antibody tests for H and M bands were positive.
Serological tests including enzyme-linked immunosorbent assay (ELISA), IHA, complement-fixation, immunofluorescence, counter electrophoresis, and double diffusion are in use.
Several different serological techniques have been proposed: complement-fixation test [4], fluorescent antibody [18,26], capillary tube agglutination test [28], rapid card agglutination test [2], indirect fluorescent antibody test [10,17] and enzyme linked immunosorbent assay (ELISA) [11,25,30,32,33].
A rising complement-fixation titer may be helpful in diagnosis, but is not always reliable in immunosuppressed patients.
The serum complement-fixation CMV titer in October 1980 was 256; in May 1981 it was 32.(*) The patient's condition deteriorated despite courses of treatment with trimethoprim-sulfamethoxazole (TMP/SMX), pentamidine, and acyclovir.
Its antigenic relationship to CTFV was established by a complement-fixation assay (7).
Complement-fixation testing of both the acute and convalescent specimens collected 7 weeks later demonstrated fourfold or greater rise in IgG measles antibody for patients 1 and 3 and a fourfold decline in measles IgG antibody for patient 2.
The results of echocardiograms and routine specialized laboratory tests, including enterovirus complement-fixation serologic screening, conducted by physicians who evaluated patients at hospitals, were recorded.

Full browser ?