A randomized trial of prolonged cotrimoxazole
in HIV-infected children in Africa.
To adhere to these guidelines, daily cotrimoxazole
preventive therapy (CPT) was implemented for mothers (480 mg 2x/d) and infants (240 mg 1x/d) enrolled in the study as of June 13, 2006, and for all those enrolled afterward.
was sensitive to amikacin, ciprofloxacin, ceftriaxone, imipenem, cotrimoxazole
, cefoperazone-sulbactam, and gentamycin.
gonorrhoeae showed moderate to high resistance (60 to 88%) to penicillin, tetracycline, cotrimoxazole
, erythromycin, ciprofloxacin and cefixime.
Susceptibility testing was carried out according to Clinical and Laboratory Standard Institute, CLSI (CLSI M100-S20-2010; M100-2017) using the commercially prepared antibiotic discs (Abtek Biologicals Ltd) with the following antibiotics; Amoxicillin (25[micro]g), Gentamicin (10[micro]g), Cotrimoxazole
(25[micro]g), Nitrofurantoin (20[micro]g), Nalidixic acid (30[micro]), Ofloxacin (5[micro]g), Augmentin (30[micro]g), Tetracycline (10[micro]g), Cloxacillin (5[micro]g), Erythromycin (5[micro]g), Streptomycin (10[micro]g) and Chloramphenicol (10[micro]g).
The only CONS isolate was sensitive only to Imipenem, nitrofurantoin, Amikacin, ceftriaxone and cotrimoxazole
Two boxes of CAMPOLAS (cotrimoxazole
, amoxicillin, mefenamic acid, paracetamol, oral rehydration solution, lagundi, vitamin A, skin ointment) amounting to Php 56,439 were distributed to the heavily affected municipalities of Hermosa and Dinalupihan.
Antibiotic susceptibility testing was determined for this isolates to routinely used antibiotics such as to piperacillintazobactam, cefotaxime, ceftazidime, tetracycline, cotrimoxazole
, aztreonam, gentamicin, and imipenem by Kirby Bauer disc diffusion method as per CLSI guideline.
The isolates were also tested for resistance to ampicillin, cotrimoxazole
, ciprofloxacin, ceftriaxone, doripenem, imipenem, ertapenem, aztreonam, moxifloxacin, cefpirome, cefepime, gatifloxacin, and chloramphenicol by Kirby-Bauer disc diffusion method.
The following antibiotic discs were tested: ceftazidime (30 [micro]g), cefepime (30 [micro]g), piperacillin-tazobactam (100 [micro]g/10 [micro]g), Imipenem (10 [micro]g), Meropenem (10 [micro]g), Gentamicin (10 [micro]g), Amikacin (30 [micro]g), Ampicillin-sulbactam (10 [micro]g/10 [micro]g), Cotrimoxazole
(25 [micro]g), aztreonam (30 [micro]g), Ciprofloxacin (5 [micro]g), Norfloxacin (30 [micro]g) (for urinary isolates), Polymyxin B (300 units), and Colistin (10 [micro]g).
was the most commonly prescribed drug (58.7%), followed by ciprofloxacillin (10.9%), amoxicillin (4.6%) and metronidazole (2%) (Table 2).