The results showed that of those currently using a COX-2 inhibitor
, 19% were more likely to die after a stroke than those who didn't take the drug and new users of the medicines had a 42% increase in risk mortality from stroke compared to nonusers.
In particular, we will examine the impact of DTCA on the time patients wait after diagnosis with OA and before initiating treatment with a COX-2 inhibitor
More specifically, the impact of the PAR for COX-2 inhibitors
on total prescription costs for recipients who switched from a COX-2 inhibitor
to an NSAID or other pain relievers was analyzed.
To test whether thwarting COX-2 would have an effect on mice predisposed to pancreatic cancer, the researchers fed chow containing a COX-2 inhibitor
called nimesulide to mice harboring the Kras mutation.
Green tea alone reduced tumor growth by 42%, and the Cox-2 inhibitor
celecoxib slowed it by 57% on its own, according to a study published in last week's issue of the journal Clinical Cancer Research.
Selective COX-2 inhibitors
have been in the news since the FDA removed the selective COX-2 inhibitor
, rofecoxib, from the market in 2004.
Vioxx, a COX-2 inhibitor
in anti-inflammatories, was banned in 2004 after it was shown that patients on the drug were more than twice as likely to have heart attacks as those not taking it.
Three studies of COX-2 inhibitors
have shown that administration of a COX-2 inhibitor
is associated with a reduction in polyps in high-risk patients.
Research has found that the Cox-2 inhibitor
celecoxib, which is used to treat arthritis and acute pain, increases by more than twofold the risk of a heart attack.
Don't write off the entire COX-2 inhibitor
class of drugs, says Dr.
A total of 40, 000 were given another Cox-2 inhibitor
, Celebrex, while others were taking ibuprofen or naproxen.
Celebrex was the first COX-2 inhibitor
, a class of medicine designed to