Crohn's disease


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Related to Crohn's disease: ulcerative colitis, colitis

Crohn's disease

 (krōnz)
n.
A form of inflammatory bowel disease that most commonly affects the ileum and colon, characterized by abdominal pain, diarrhea, and thickening of the bowel wall.

[After Burrill Bernard Crohn (1884-1983), American physician.]

Crohn's disease

(krəʊnz)
n
(Pathology) inflammation, thickening, and ulceration of any of various parts of the intestine, esp the ileum. Also called: regional enteritis See also Johne's disease
[C20: named after B. B. Crohn (1884–1983), US physician]

Crohn's′ disease`

(kroʊnz)
n.
a chronic inflammatory bowel disease that causes scarring and thickening of the intestinal walls and frequently leads to obstruction. Also called ileitis.
[after Burrill Bernard Crohn (1884–1983), U.S. physician]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.Crohn's disease - a serious chronic and progressive inflammation of the ileum producing frequent bouts of diarrhea with abdominal pain and nausea and fever and weight loss
colitis, inflammatory bowel disease - inflammation of the colon
References in periodicals archive ?
Crohn's disease can affect any part of the digestive system but often the small intestine.
Crohn's disease was defined for a first-listed diagnosis field and for any of 15 diagnosis fields during 2003-2008 and 25 fields during 2009-2013 with International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) disease codes 555.
Galapagos NV (AMS: GLPG) will begin two new Phase 2 studies that will investigate filgotinib in small bowel Crohn's disease and fistulising Crohn's disease, with filgotinib collaboration partner Gilead Sciences Inc (NASDAQ: GILD) leading the studies, the company revealed on Friday.
The report provides comprehensive information on the therapeutics under development for Crohn's Disease (Regional Enteritis), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type.
HUMIRA is currently approved in the European Union for the treatment of severe active Crohn's disease in pediatric patients (from six years of age) who have had an inadequate response to conventional therapy including primary nutrition therapy, a corticosteroid, and an immunomodulator, or who are intolerant to or have contraindications for such therapies.
1) In addition, a significant reduction in total disaccharidase activity was found in the jejunum of patients with Crohn's disease who had no radiologic evidence of small-bowel involvement.
Twenty-eight gastroenterology centers across North America have been working together to uncover how microbes contribute to the inflammatory cascade of Crohn's disease.
It would allow the identification of patient subpopulations and biotypes within the Crohn's disease spectrum and the application of targeted chemotherapeutic treatments that go beyond supportive in nature.
attempted to determine the effect that regular medical marijuana use had on patients with Crohn's disease, (http://www.
AbbVie supports the start of this innovative study in Crohn's disease with GLPG0634.
Metastatic cutaneous Crohn's disease of the nipple: report of a case.
The existing dental and medical literature documents a broad spectrum of oral Crohn's disease (OCD) manifestations in adults and children [Williams et al.