Crohn's disease


Also found in: Thesaurus, Medical, Acronyms, Encyclopedia, Wikipedia.
Related to Crohn's disease: ulcerative colitis, colitis

Crohn's disease

 (krōnz)
n.
A form of inflammatory bowel disease that most commonly affects the ileum and colon, characterized by abdominal pain, diarrhea, and thickening of the bowel wall.

[After Burrill Bernard Crohn (1884-1983), American physician.]

Crohn's disease

(krəʊnz)
n
(Pathology) inflammation, thickening, and ulceration of any of various parts of the intestine, esp the ileum. Also called: regional enteritis See also Johne's disease
[C20: named after B. B. Crohn (1884–1983), US physician]

Crohn's′ disease`

(kroʊnz)
n.
a chronic inflammatory bowel disease that causes scarring and thickening of the intestinal walls and frequently leads to obstruction. Also called ileitis.
[after Burrill Bernard Crohn (1884–1983), U.S. physician]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.Crohn's disease - a serious chronic and progressive inflammation of the ileum producing frequent bouts of diarrhea with abdominal pain and nausea and fever and weight loss
colitis, inflammatory bowel disease - inflammation of the colon
References in periodicals archive ?
Complications from Crohn's disease include intestinal obstruction or fistulas, abscesses, ulcers, and ultimately malnutrition as the body is not receiving adequate nutrients.
Ulcerative colitis and Crohn's disease are long-term conditions that involve inflammation of the gut.
In this study, patients with moderately- to severely active Crohn's disease were randomized to receive either placebo or one of three doses of mirikizumab, which is an investigational antibody that targets the p19 subunit of interleukin 23.
Ulcerative colitis affects the large intestine and causes irritation and swelling called inflammation whereas Crohn's disease is a chronic inflammatory bowel disease (IBD) characterised by inflammation that responds to tissue injury ultimately causing redness, swelling, and pain.
People with Crohn's disease commonly experience phases of intense abdominal pain, exhaustion, bloody diarrhoea, sore, swollen joints and a number of other unpleasant symptoms behind closed doors.
High-risk HPV and HPV strain 16 were detected in 30% of patients with Crohn's disease and 18% of patients without Crohn's disease (P = .005), said Lucine Vuitton, MD, of University Hospital of Besancon (France) and her associates.
Perianal fistulas constitute the most frequent (23%-38%) and seriously morbid type of the perianal Crohn's disease. The basic aim of perianal Crohn's disease therapy is to cure the disease and to improve the quality of life of patients by combining medical and surgical methods (3).
Biopharmaceutical company TiGenix NV (Euronext Brussels:TIG)(NASDAQ:TIG) and Takeda Pharmaceutical Company Limited (TSE:4502) on Friday jointly announced the receipt of approval from the European Commission (EC) for Alofisel for the treatment of complex perianal fistulas in Crohn's disease, a chronic inflammatory disease of the intestine.
Theravance plans to initiate a Phase IIb/in adaptive design study in ulcerative colitis with TD-1473 and is planning to initiate a Phase n study in Crohn's disease this year.
Crohn's disease is considered to be a multifactorial disease with both genetic and acquired factors in its aetiology.
Inflammatory bowel disease (IBD) describes two conditions: ulcerative colitis and Crohn's disease.