Cryptopine


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Cryp´to`pine


n.1.(Chem.) A colorless crystalline alkaloid obtained in small quantities from opium.
Webster's Revised Unabridged Dictionary, published 1913 by G. & C. Merriam Co.
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Once the molecular formulae were generated and the UV-Vis results contrasted, the MS/MS fragmentation patterns were studied and compared with those in databases, but only experimental MS/MS spectra of protopine and cryptopine were found (Table S2).
Compounds are numbered according to Table 2: (1) pallidine; (2) isoboldine derivative; (3) N,N-dimethylcoclaurine (4) fumaritine; (5) coclaurine; (6) N-methylcoclaurine; (7) magnoflorine; (8) reticuline; (9) parfumine; (10) parfumidine; (11) isoboldine; (12) coreximine; (13) methylcoreximine 1; (14) methylcoreximine 2; (15) cheilanthifoline; (16) dehydrocheilanthifoline; (17) demethyleneberberine/jatrorubine; (18) cryptopine; (19) protopine; (20) fumariline; (21) stylopine; (22) coptisine; (23) corysamine; (24) impatien C; (25) dihydrosanguinarine; (26) 8-oxocoptisine.
The analysis confirmed the presence of cryptopine in Chelidonium majus but not in F.
These were cryptopine in Chelidonium majus; N,N- dimethylhernovine in Meconopsis cambrica, Berberis thunbergii, Mahonia aquifolium, Corydalis cava, Glaucium flavum, and Chelidonium majus; methyl-hernovine in Glaucium flavum; columbamine in Berberis thunbergii; methyl-corypalmine, chelidonine, and sanguinarine in Fumaria officinalis; and sanguinarine in Corydalis cava.
1986 6.61 15 Dehydrocheilanthifoline Tanahashi and Zenk, 2.01 1985 16 Demethyleneberberine/ 0.50 jatrorubine 17 Cryptopine Sousek et al.
However, cryptopine (3), allocryptopine (4), scoulerine (26), mecambridine (27), 2,3,10,11-tetramethoxyberbine (28), 8-ethyl-2,3,10,11-tetramethoxyberbine (29) and 2,3-dimethoxyberbine (36) had some selectivity towards CYP2D6, and these compounds add to the list of known CYP2D6 ligands (Lewis 2004; Wang et al.