mycosis fungoides

(redirected from Cutaneous T-cell Lymphoma)
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Related to Cutaneous T-cell Lymphoma: mycosis fungoides, Sezary syndrome
Translations

mycosis fungoides

n micosis f fungoide
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References in periodicals archive ?
Schaber, PhD, will deliver a corporate presentation to review upcoming potential milestones for the Company's two pivotal phase 3 clinical programs in cutaneous T-cell lymphoma and oral mucositis in head and neck cancer at the RHK Capital 2019 Disruptive Growth Conference on Wednesday, September 4, 2019 at 9:20 AM EDT.
Food and Drug Administration later this quarter to discuss a proposed pivotal trial of intratumoral TTI-621 in patients with cutaneous T-cell lymphoma. We have enrolled patients under our amended TTI-621 intravenous protocol that will allow us to dose cutaneous T-cell lymphoma patients beyond 0.5 mg/kg." As of June 30, 2019, Trillium had a combined cash and cash equivalents and marketable securities balance of $42.8M, compared to $45.4M at December 31, 2018.
MAVORIC is the first pivotal trial in cutaneous T-cell lymphoma (CTCL) to use progression free survival (PFS) as a primary endpoint.
Tinostamustine is currently being studied in multiple myeloma, Hodgkin lymphoma, peripheral T-cell lymphoma, cutaneous T-cell lymphoma, T-cell prolymphocytic leukemia, soft tissue sarcoma, small cell lung cancer, triple-negative breast cancer, ovarian cancer, endometrial cancer and MGMT-unmethylated glioblastoma.
Primary cutaneous follicular helper T-cell lymphoma: a new subtype of cutaneous T-cell lymphoma reported in a series of 5 cases.
The most common types of cutaneous T-cell lymphoma are mycosis fungoides and Sezary syndrome.
Currently, Medivir's clinical pipeline consists of four projects, namely remetinostat for cutaneous T-cell lymphoma (phase II); birinapant in combination with Keytruda for solid tumours (phase I); MIV-818, a nucleotide prodrug for liver cancer that recently entered into a phase I clinical trial and MIV-711, an osteoarthritis candidate drug with fresh and promising data from the recent phase IIa extension study.
Although researchers have long suspected viruses of a role in primary cutaneous lymphomas, "all of the so-far-suspected viruses including retroviruses, herpesviruses, and polyomaviruses have failed to reveal a consistent association with both cutaneous B-cell lymphoma [CBCL] and cutaneous T-cell lymphoma [CTCL]," wrote Alexander Kreuter, MD, of the department of dermatology, venereology, and allergology at Helios St.
There are four types of Hodgkin's lymphoma -- chronic lymphocytic leukemia, cutaneous B-cell lymphoma, cutaneous T-cell lymphoma and lymphoma. The lymphoid tissue includes lymph nodes, lymph vessels, spleen, bone marrow, thymus, adenoids and tonsils, and digestive tract.
(2) Regarding the pathophysiology of MF and cutaneous T-cell lymphoma, antigenic stimulation was first proposed more than 20 years ago.
The proapoptotic protein Bax is also expressed at high levels in CD30+ cutaneous lymphoproliferative diseases and may play a crucial role in mediating apoptosis of tumor cells.9 The CD30+ cutaneous lymphoproliferative disorders account for approximately 25% of cutaneous T-cell lymphoma cases.10 Black persons may be less affected by lymphomatoid papulosis than persons of other racial groups.