cyclooxygenase

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cy·clo·ox·y·gen·ase

 (sī′klō-ŏk′sĭ-jə-nās′, -nāz′)
n.
1. See COX-1.
2. See COX-2.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.cyclooxygenase - either of two related enzymes that control the production of prostaglandins and are blocked by aspirin
enzyme - any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions
Cox-1, cyclooxygenase-1 - an enzyme that regulates prostaglandins that are important for the health of the stomach lining and kidneys; "an unfortunate side effect of NSAIDs is that they block Cox-1"
Cox-2, cyclooxygenase-2 - an enzyme that makes prostaglandins that cause inflammation and pain and fever; "the beneficial effects of NSAIDs result from their ability to block Cox-2"
References in periodicals archive ?
Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas.
Cyclooxygenase 2 selective inhibitors in cancer treatment and prevention.
In animal models, the cyclooxygenase 2 inhibitor celecoxib, better known by its brand name Celebrex, inhibits the development of ultraviolet-induced pre-malignant skin papillomas, which are thought to correspond to actinic keratoses, the pre-malignant precursor of non-melanoma skin cancers