Cox-2 inhibitor

(redirected from Cyclooxygenase-2 selective inhibitor)
Also found in: Thesaurus, Medical, Encyclopedia.

COX-2 inhibitor

n.
Any of a class of nonsteroidal anti-inflammatory drugs that selectively block prostaglandin formation so as to cause minimal gastrointestinal side effects.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.Cox-2 inhibitor - an anti-inflammatory drug that fights pain and blocks Cox-2 activity without impeding the activity of Cox-1; increases the risk of heart attacks; "Cox-2 inhibitors reduce the symptoms of arthritis without endangering the stomach and kidneys"
anti-inflammatory, anti-inflammatory drug - a medicine intended to reduce inflammation
Celebrex, celecoxib - a Cox-2 inhibitor (trade name Celebrex) that relieves pain and inflammation without harming the digestive tract
rofecoxib, Vioxx - a Cox-2 inhibitor (trade name Vioxx) that relieves pain and inflammation without harming the digestive tract; voluntarily withdrawn from the market in 2004
Bextra, valdecoxib - a Cox-2 inhibitor (trade name Bextra) that relieves pain and inflammation without harming the digestive tract
References in periodicals archive ?
He reported on 8,076 rheumatoid arthritis patients randomized to the cyclooxygenase-2 selective inhibitor rofecoxib at 50 mg/day or to 400 mg b.
The role of cyclooxygenase-2 selective inhibitors (coxibs) and most NSAIDs in most CVD is not well established and needs further investigation; therefore, these agents should be prescribed with caution.

Full browser ?