cystic fibrosis

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Related to Cystic fibrosis allele: Recessive allele

cystic fibrosis

n. Abbr. CF
A genetic disease that involves dysfunction of the exocrine glands and affects many organs and organ systems, especially the respiratory system, the pancreas, the intestines, the sweat glands, and, in males, the reproductive system. It is characterized by the chronic accumulation of thick mucus in the lungs and pancreas, affecting breathing and digestion, and by recurring infections. Also called mucoviscidosis.

cystic fibrosis

n
(Pathology) an inheritable disease of the exocrine glands, controlled by a recessive gene: affected children inherit defective alleles from both parents. It is characterized by chronic infection of the respiratory tract and by pancreatic insufficiency

cys′tic fibro′sis


n.
a hereditary disease of the exocrine glands characterized by the production of thickened mucus that chronically clogs the bronchi and pancreatic ducts, leading to breathing difficulties, infection, and fibrosis.
[1950–55]

cys·tic fi·bro·sis

(sĭs′tĭk fī-brō′sĭs)
An inherited disease of certain glands, causing them to produce abnormally large amounts of thick mucus. It affects especially the pancreas and the mucus-secreting glands of the lungs, and results in problems with breathing and digestion.

cystic fibrosis

An inherited disease that involves oversecretion of a heavy mucus (thick, slimy fluid) that clogs the respiratory passages. Sufferers are more prone to catching fatal respiratory infections.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.cystic fibrosis - the most common congenital disease; the child's lungs and intestines and pancreas become clogged with thick mucus; caused by defect in a single gene; no cure is known
monogenic disease, monogenic disorder - an inherited disease controlled by a single pair of genes
fibrosis - development of excess fibrous connective tissue in an organ
Translations

cystic fibrosis

cys·tic fi·bro·sis

[MIM*219700]
n. fibrosis cística del páncreas, fibroquiste.

cystic fibrosis

n fibrosis quística
References in periodicals archive ?
5% of the mutations in 200 Belgian cystic fibrosis alleles by reversedot-blot and sequencing of the complete coding region and exon/ intron junctions of the CFTR gene.
Characterization of more than 85% of cystic fibrosis alleles in the Greek population, including five novelmutations.
Simultaneous detection of AF508, G542X, NI303K, G551D and 1717-IG-A cystic fibrosis alleles by a multiplex DNA enzyme immunoassay.

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