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Of, relating to, or producing a toxic effect on cells.

cy′to·tox·ic′i·ty (-tŏk-sĭs′ĭ-tē) n.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(ˌsaɪ toʊ tɒkˈsɪs ɪ ti)

cell destruction caused by a cytotoxin.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.cytotoxicity - the degree to which something is toxic to living cells
toxicity - the degree to which something is poisonous
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.


n. citotoxicidad, la capacidad de un agente de destruir ciertas células.
English-Spanish Medical Dictionary © Farlex 2012
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Onvansertib has demonstrated synergy in preclinical studies with numerous chemotherapies and targeted therapeutics used to treat leukemias, lymphomas and solid tumor cancers, including irinotecan, FLT3 and HDAC inhibitors, taxanes and cytotoxins. Trovagene believes the combination of onvansertib with other compounds has the potential to improve clinical efficacy in acute myeloid leukemia (AML), metastatic castration-resistant prostate cancer (mCRPC), non-Hodgkin lymphoma (NHL), colorectal cancer and triple-negative breast cancer (TNBC), as well as other types of cancer.
As this involves handling of highly potent cytotoxins, it will require the conjugation and purifications is carried out by integrated bioconjugation CDMOs.
ASN100 is a combination of two fully human monoclonal antibodies that together neutralize the six cytotoxins critical to S.
Being cytotoxins, the polyphenols inhibit cancer cells from mutating and induce "apoptosis" causing their natural death which, otherwise, is impossible without a medical intervention such as chemotherapy, radiation and surgery.
Upon internalization of the ADC, the antibody-bound cytotoxins are released intracellularly, leading to programmed tumor cell death.
Though longstanding knowledge of cytotoxins in spitting elapids exists, the presence of powerful cytotoxins has also been well investigated and documented in nonspitting elapids.
Puri, "Novel anti-brain tumor cytotoxins specific for cancer cells," Nature Biotechnology, vol.
cholerae and Helicobacter pylori are known for their ability to produce vacuolating cytotoxins demonstrating the association between biological effects (vacuolation) and pathogenicity caused by these microorganisms.
Staphylococcus aureus is known to secrete virulence factors including cytotoxins, superantigens, lipases, and proteases that activate inflammatory cells and can cause significant skin barrier dysfunction.