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Related to D-penicillamine: Cuprimine


A chelating agent, C5H11NO2S, that is a degradation product of penicillin and is used in the treatment of Wilson disease, refractory rheumatoid arthritis, and excess urinary excretion of cystine.


(Pharmacology) pharmacol a metabolite of penicillin, being a pyridoxine inhibitor and chelating agent, usually used as an anti-inflammatory in the treatment of arthritis


(ˌpɛn əˈsɪl əˌmin, -mɪn)

a chelating agent produced by the degradation of penicillin, used esp. to treat rheumatoid arthritis and lead poisoning.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.penicillamine - a drug (trade name Cuprimine) used to treat heavy metal poisoning and Wilson's disease and severe arthritis
medicament, medication, medicinal drug, medicine - (medicine) something that treats or prevents or alleviates the symptoms of disease
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References in periodicals archive ?
Copper chelation by D-penicillamine generates reactive oxygen species that are cytotoxic to human leukemia and breast cancer cells.
Pemphigus vulgaris induced by D-penicillamine therapy in a patient with systemic sclerosis.
Although no longer used routinely in rheumatology, D-penicillamine has been used for Wilson's disease, scleroderma, rheumatoid arthritis, and cystinuria.
It also can be associated with malignancy, D-penicillamine therapy, nephrotic syndrome, hypothyroidism, and AIDS.