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Findings confirm reports that whole breast radiation therapy (WBRT) may be safely omitted in patients with low-risk DCIS.
DCIS represents a continuum of conditions with different clinical presentations and histological behavior.
All missed foci of microinvasion and invasion, both cases of DCIS downgraded to atypical ductal hyperplasia, and a case of DCIS involving sclerosing adenosis on surgical excision were identified in this manner.
Previously, EPC was thought be a form of DCIS but in DCIS myo epithelial layer at the periphery of the duct remains intact.
Gina Kolata at The New York Times wrote that DCIS posed little or no risk: "Patients with this condition had close to the same likelihood of dying of breast cancer as women in the general population.
DCMs are designed to deploy two NATO DCIS teams simultaneously- one major and one minor.
Mortality also was related to adverse DCIS characteristics such as grade, size, comedo-necrosis, and lack of an estrogen receptor.
Based on recent studies in the New England Journal of Medicine and the BMJ, they used an overdiagnosis rate of 22% for the breast cancer estimate; the overdiagnosis rate of 86% for DCIS came from a 2004 study.
1) in the surrounding breast including presence of DCIS or LCIS.
4,5] On other hand, patients with DCIS should be treated by surgical removal of the lesion, with clear margins followed by radiotherapy, or mastectomy.
Data source: A phase II, double-blind, placebo-controlled study compared antiproliferative effects, breast tissue and plasma levels of 4-OHT, and coagulation parameters in 26 women with DCIS, randomized to daily treatment with 4-OHT gel applied to both breasts or oral tamoxifen, after 6-10 weeks of treatment, ending the day before surgical excision.
DCIS means cells inside some of the ducts of the breast have started to turn into cancer cells.
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