DNA

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DNA
A. adenine
T. thymine
C. cytosine
G. guanine

DNA

 (dē′ĕn-ā′)
n.
A nucleic acid that carries the genetic information in cells and some viruses, consisting of two long chains of nucleotides twisted into a double helix and joined by hydrogen bonds between the complementary bases adenine and thymine or cytosine and guanine. DNA sequences are replicated by the cell prior to cell division and may include genes, intergenic spacers, and regions that bind to regulatory proteins.

[d(eoxyribo)n(ucleic) a(cid).]

DNA

n
(Biochemistry) deoxyribonucleic acid; a nucleic acid that is the main constituent of the chromosomes of all organisms (except some viruses). The DNA molecule consists of two polynucleotide chains in the form of a double helix, containing phosphate and the sugar deoxyribose and linked by hydrogen bonds between the complementary bases adenine and thymine or cytosine and guanine. DNA is self-replicating, plays a central role in protein synthesis, and is responsible for the transmission of hereditary characteristics from parents to offspring. See also genetic code
abbreviation for
did not attend

DNA

deoxyribonucleic acid: an extremely long, double-stranded nucleic acid molecule arranged as a double helix that is the main constituent of the chromosome and that carries the genes as segments along its strands: found chiefly in the chromatin of cells and in many viruses.
[1930–35]
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DNA

(dē′ĕn-ā′)
Short for deoxyribonucleic acid. The nucleic acid that is the genetic material determining the makeup of all living cells and many viruses. It consists of two strands of nucleotides linked together in a structure resembling a ladder twisted into a spiral. In eukaryotic cells, the DNA is contained mainly in the nucleus and mitochondria. DNA can replicate itself and synthesize RNA. Compare RNA. See Note at gene.
Did You Know? One of the wonders of nature is that the complexity and diversity of life can be contained in a molecule with a relatively simple structure. Deoxyribonucleic acid, commonly called DNA, exists mainly in the nucleus and mitochondria of each cell in an organism. It consists of two long strands linked together in a structure resembling a ladder twisted into a spiral, called a double helix. Each rung is made up of two chemical bases, called nucleotides, that are joined together by hydrogen bonds. There are four kinds of nucleotides in a DNA molecule: cytosine, guanine, adenine, and thymine—C, G, A, and T, for short. Specific sequences of these bases, known as genes, form codes that contain all of an organism's genetic information. When other components of a cell "read" this code, they produce proteins, the building blocks of life.

DNA

deoxyribonucleic acid.
See also: Heredity
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.DNA - (biochemistry) a long linear polymer found in the nucleus of a cell and formed from nucleotides and shaped like a double helixDNA - (biochemistry) a long linear polymer found in the nucleus of a cell and formed from nucleotides and shaped like a double helix; associated with the transmission of genetic information; "DNA is the king of molecules"
cistron, gene, factor - (genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors"
operon - a segment of DNA containing adjacent genes including structural genes and an operator gene and a regulatory gene
biochemistry - the organic chemistry of compounds and processes occurring in organisms; the effort to understand biology within the context of chemistry
base pair - one of the pairs of chemical bases joined by hydrogen bonds that connect the complementary strands of a DNA molecule or of an RNA molecule that has two strands; the base pairs are adenine with thymine and guanine with cytosine in DNA and adenine with uracil and guanine with cytosine in RNA
adenine, A - (biochemistry) purine base found in DNA and RNA; pairs with thymine in DNA and with uracil in RNA
cDNA, complementary DNA - single-stranded DNA that is complementary to messenger RNA or DNA that has been synthesized from messenger RNA by reverse transcriptase
episome - DNA that is not incorporated into the genome but is replicated together with the genome (especially in bacterial cells)
cytosine, C - a base found in DNA and RNA and derived from pyrimidine; pairs with guanine
coding DNA, exon - sequence of a gene's DNA that transcribes into protein structures; "exons are interspersed with introns"
intron, noncoding DNA - sequence of a eukaryotic gene's DNA that is not translated into a protein
junk DNA - stretches of DNA that do not code for genes; "most of the genome consists of junk DNA"
recombinant deoxyribonucleic acid, recombinant DNA - genetically engineered DNA made by recombining fragments of DNA from different organisms
sticky end - an end of DNA in which one strand of the double helix extends a few units beyond the other
jumping gene, transposon - a segment of DNA that can become integrated at many different sites along a chromosome (especially a segment of bacterial DNA that can be translocated as a whole)
guanine, G - a purine base found in DNA and RNA; pairs with cytosine
nucleic acid - (biochemistry) any of various macromolecules composed of nucleotide chains that are vital constituents of all living cells
polymer - a naturally occurring or synthetic compound consisting of large molecules made up of a linked series of repeated simple monomers
T, thymine - a base found in DNA (but not in RNA) and derived from pyrimidine; pairs with adenine
Translations
DNA
DNA
DNA
DNA
DNK
DNA
디옥시리보핵산
DNA
รหัสทางพันธุกรรม
DNA

DNA

A. N ABBR =deoxyribonucleic acidADN m
B. CPD DNA fingerprinting, DNA profiling Nidentificación f mediante el análisis del ADN
DNA testing Npruebas fpl del ADN

DNA

[ˌdiːɛnˈeɪ] (=deoxyribonucleic acid)
nADN m
modif [analysis, database, evidence, profile, sample] → d'ADNDNA fingerprinting nanalyse f de l'empreinte génétiqueDNA sequence nséquence f d'ADNDNA test ntest m ADNDNA testing ntests mpl ADN

DNA

abbr of de(s)oxyribonucleic acidDNS f

DNA

:
DNA fingerprinting, DNA profiling
DNA test
n (Med) → Gentest m
DNA testing
nDNS-Tests pl

DNA

[diːɛnˈeɪ] n abbr =deoxyribonucleic acidDNA m

DNA

الـحِمْضُ النَوَوِيّ DNA DNA DNS DNA ADN DNA ADN DNK DNA DNA 디옥시리보핵산 DNA DNA DNA ADN, DNA ДНК DNA รหัสทางพันธุกรรม DNA DNA 脱氧核糖核酸

DNA

V. deoxyribonucleic acid.
References in periodicals archive ?
Cancers with mutations causing defective DNA repair systems tend to be more dependent on PARP than cancers with intact repair systems.
Alpha-synuclein's role in DNA repair may be crucial in preventing cell death.
Preclinical data indicate that combining talazoparib with ZEN-3694 is a rational combination to test in patients that are proficient in homologous DNA repair. BETi have been shown pre-clinically to modulate homologous DNA repair genes and can thus potentially sensitize BRCA1/2 proficient patients to talazoparib.
XP is a rare, recessive disorder of DNA repair. Affected individuals are unable to repair ultraviolet radiation (UVR)-induced DNA damage, leading to a variety of clinical manifestations: a dramatic increase in skin cancers and small, pigmented spots on the skin with clearly defined edges, an exaggerated response to sun exposure and neurodegeneration (degeneration of the nervous system, especially the neurons in the brain) in approximately 30 percent of affected individuals.
Defects in dna repair trigger a number of devastating health complications ranging from developmental abnormalities to the premature onset of age-related diseases, including the metabolic syndrome, neurodegeneration and cancer.
The study, published in the Anesthesia academic journal, shows that DNA repair gene expression is lower at baseline among night workers and further decreases after acute sleep deprivation, which supports the postulation that night workers demonstrate impaired DNA repair.
PARP inhibitors block an additional DNA repair pathway, and the anti-tumor effects of PARP inhibitors can be intensified in patients with BRCA mutations.
The grant, awarded by the National Institute of General Medical Sciences, will provide Pezza with $1.4 million to better understand how errors in DNA repair result in serious health consequences.
Additionally, DNA repair activity and the abundance of repair proteins, XPC and OGG1/2, in lung tissues are reduced by tobacco smoke.
Onxeo SA (CPH:ONXEO) (Paros:ONXEO), a French, clinical-stage biotechnology company specialising in the development of drugs in oncology, announced on Thursday new positive results from preclinical studies of AsiDNA, its first-in-class DNA Repair inhibitor, in combination with PARP inhibitors (PARPi).
Protecting ATP (adenosine-triphosphate) helps promote continuous DNA repair mechanisms.
In mammalian cells, numerous predominant DNA repair mechanisms are well analyzed, such as direct repair, base excision repair (BER), nucleotide excision repair (NER), mismatch repair, homologous recombination repair (HR), and non-homologous end-joining repair (NHEJ) [11].