As a result, approximately 123 million children, 91% of the global population of surviving infants, received at least 1 dose of DTP vaccine
during their first year of life in 2016, and nearly 117 million (86%) completed the DTP series.
Until the 1990s, the DTP vaccine
, which includes a whole pertussis bacterium, was highly effective at preventing pertussis but could cause febrile seizures, an adverse event that proved too intolerable for many families.
4) Prior to this, the suggestion in the 1970s that the DTP vaccine
was related to infant brain damage resulted in vaccination rates for the DTP vaccine
dropping to 30% in Britain, (5) a situation that led to three major outbreaks of whooping cough over a 12-year period, 300,000 notifications and over 70 deaths.
Rounding out this troubling trilogy, on April 19, 1982, an NBC affiliate aired an Emmy-winning, hour-long television documentary titled DPT: Vaccine Roulette, (115) With footage of dead infants and convulsing children, the broadcast charged that the pertussis component in the DTP vaccine
(which protects against whooping cough) had not been adequately tested and could cause "damage to a devastating degree.
While measles, BCG, and smallpox vaccines have beneficial nonspecific effects, DTP vaccine
appears to have a negative effect, particularly in females.
Immunization visits are scheduled for 6 10 and 14 wks of age when DTP vaccine
and OPV are administered.
About 10 million children still do not receive the third dose of DTP vaccine
in the Region.
In 1991, DTP vaccine
was licensed in the United States.
Of the children with records of DTP vaccine
, 99% were titer positive for diphtheria antibody and 88% were titer positive for tetanus.
The UK primary vaccine schedule consisted of 3 doses of Hib conjugate vaccine, DTP vaccine
, oral polio vaccine, and MCC vaccine all administered at 2, 3, and 4 months of age.
GSK plans to conduct clinical R&D for four products in India in 2005--two vaccines for rotavirus, one for cervical cancer, and a combination DTP vaccine
Contrary to the expectation, the researchers, writing in the journal Paediatrics, said the figures appeared to show that the earlier the child was immunised with the DTP vaccine
, the fewer the problems reported as they got older.