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 (dâr′ē-ĕn′, där-yĕn′)
A region of eastern Panama on the Gulf of Darién, a wide bay of the Caribbean Sea between eastern Panama and northwest Colombia. In 1513 Vasco Núñez de Balboa led an expedition across the Isthmus of Darién (now the Isthmus of Panama) and became the first European to reach the west coast of the Americas.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(ˈdɛərɪən; ˈdæ-)
1. (Placename) the E part of the Isthmus of Panama, between the Gulf of Darien on the Caribbean coast and the Gulf of San Miguel on the Pacific coast; chiefly within the republic of Panama but extending also into Colombia: site of a disastrous attempt to establish a Scottish colony in 1698
2. (Placename) Isthmus of Darien the former name of the Isthmus of Panama
Spanish name: Darién
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


or Dar•ién


Gulf of, an arm of the Caribbean between NE Panama and NW Colombia.
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