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 (dâr′ē-ĕn′, där-yĕn′)
A region of eastern Panama on the Gulf of Darién, a wide bay of the Caribbean Sea between eastern Panama and northwest Colombia. In 1513 Vasco Núñez de Balboa led an expedition across the Isthmus of Darién (now the Isthmus of Panama) and became the first European to reach the west coast of the Americas.


(ˈdɛərɪən; ˈdæ-)
1. (Placename) the E part of the Isthmus of Panama, between the Gulf of Darien on the Caribbean coast and the Gulf of San Miguel on the Pacific coast; chiefly within the republic of Panama but extending also into Colombia: site of a disastrous attempt to establish a Scottish colony in 1698
2. (Placename) Isthmus of Darien the former name of the Isthmus of Panama
Spanish name: Darién


or Dar•ién


Gulf of, an arm of the Caribbean between NE Panama and NW Colombia.
References in classic literature ?
So that when I shall hereafter detail to you all the specialities and concentrations of potency everywhere lurking in this expansive monster; when I shall show you some of his more inconsiderable braining feats; I trust you will have renounced all ignorant incredulity, and be ready to abide by this; that though the Sperm Whale stove a passage through the Isthmus of Darien, and mixed the Atlantic with the Pacific, you would not elevate one hair of your eye-brow.
South America is a place I love, and I think, if you take it right through from Darien to Fuego, it's the grandest, richest, most wonderful bit of earth upon this planet.
There was a place, Now not, though Sin, not Time, first wraught the change, Where TIGRIS at the foot of Paradise Into a Gulf shot under ground, till part Rose up a Fountain by the Tree of Life; In with the River sunk, and with it rose Satan involv'd in rising Mist, then sought Where to lie hid; Sea he had searcht and Land From EDEN over PONTUS, and the Poole MAEOTIS, up beyond the River OB; Downward as farr Antartic; and in length West from ORANTES to the Ocean barr'd At DARIEN, thence to the Land where flowes GANGES and INDUS: thus the Orb he roam'd With narrow search; and with inspection deep Consider'd every Creature, which of all Most opportune might serve his Wiles, and found The Serpent suttlest Beast of all the Field.
The Darien Scheme of 1698 was Scotland's attempt at creating an international trading company to rival those of the English and Dutch.
Tavant Technologies has been selected by Darien Rowayton Bank (DRB) to create an advanced retail mortgage platform as the bank enters the national consumer mortgage sector, the company said.
Available in both jacketless hardcover and Kindle editions, Darien and the Seed of Obreget is the second novel in a fantastic series following Darien, a young girl caught between worlds in more ways than one.
Bodkin said, “This Darien Gap expedition has been singled out as a Sunday Times 'Wildest Trip of the Year' (2014).
Desto recently named Darien, of Charlton, and Justyna, of Dudley, for the 2014-2015 Massachusetts Association of School Superintendents Award of Academic Excellence.
The Empire Strikes Back: the Military Expeditions of Antonio Caballero y Gongora to the Darien (1784-1790)
The special education department at Darien Public Schools changed student individualized education plans (IEPs) outside of planning and placement team (PPT) meetings with parents, violating state and federal law, according to the state investigation.