Tattoo lymphadenitis and
dermatopathic lymphadenopathy (DLN) are the two common benign entities that can often mimic metastatic melanoma.
Sixteen of all the patients were diagnosed with reactive hyperplasia, 4 with Hodgkin lymphoma, 3 with non-Hodgkin lymphoma, one with langerhans cell histiocytosis, one with
dermatopathic lymphadenitis and one patient was diagnosed with Kikuchi Fujimato disease (Table II).
To the Editor:
Dermatopathic lymphadenitis (DL) represents a rare benign lymphatic hyperplasia commonly associated with exfoliative or eczematoid dermatitis.
Dermatopathic lymphadenopathy is characterized by an expanded paracortex with small lymphocytes and scattered Langerhans cells and histiocytes, sometimes accompanied by pigment.
Dermatopathic lymphadenitis is often observed in such patients (12).
When a cytologic specimen demonstrates prominent longitudinal nuclear grooving, a wide range of pathologic lesions should be considered, such as
dermatopathic lymphadenopathy.
Histological grades LN0-LN2 were considered to represent
dermatopathic lymphadenopathy (DL) with isolated or small clusters of atypical cells (one case had no atypical cells/LNO).
Group 2 included 13 patients diagnosed as reactive lymphadenopathy (LAP) (n = 5), granulomatous inflammation (n = 5),
dermatopathic LAP (n = 1), benign mixed tumor (n = 1) and Kikuchi's disease (n = 1).
Clonal rearrangements of T-cell receptor genes in mycosis fungoides and
dermatopathic lymphadenopathy.
In 17 patients of enlarged lymph node, FNAC was done in 13 patients and findings were suggestive of
dermatopathic lymphadenopathy.
Occasionally, this finding may be accompanied by other prominent reactive morphologic features, including florid follicular hyperplasia or
dermatopathic change.
87.5% of the cases (7 cases) revealed
dermatopathic lymphadenopathy, while 12.5% case (1 case) revealed malignancy (NHL).