To the Editor: Dermatopathic
lymphadenitis (DL) represents a rare benign lymphatic hyperplasia commonly associated with exfoliative or eczematoid dermatitis.
lymphadenopathy is characterized by an expanded paracortex with small lymphocytes and scattered Langerhans cells and histiocytes, sometimes accompanied by pigment.
5% of the cases (7 cases) revealed dermatopathic
lymphadenopathy, while 12.
lymphadenitis is often observed in such patients (12).
When a cytologic specimen demonstrates prominent longitudinal nuclear grooving, a wide range of pathologic lesions should be considered, such as dermatopathic
Group 2 included 13 patients diagnosed as reactive lymphadenopathy (LAP) (n = 5), granulomatous inflammation (n = 5), dermatopathic
LAP (n = 1), benign mixed tumor (n = 1) and Kikuchi's disease (n = 1).
samples MCPyV Pathologic feature tested positive Benign lymph nodes 110 11 (10) Acute lymphadenitis 1 0 Atypical hyperplasia 2 0 Dermatopathic
lymphadenopathy 3 0 Florid follicular hyperplasia 1 0 Mycobacterium avium-intracellulare infection 2 0 Necrotizing granulomas 3 0 Normal lymph node 29 3 (10.
Clonal rearrangements of T-cell receptor genes in mycosis fungoides and dermatopathic
All the 7 lymphnodes were negative for malignancy and showed the features of dermatopathic