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Related to Desirudin: Lepirudin


 (hîr-o͞od′n, hîr′ə-dən, -yə-)
A substance secreted by the buccal glands of leeches, capable of preventing coagulation by inactivating thrombin and used in medicine as an anticoagulant.

[Originally a trademark, from Latin hirūdō, leech.]


(Pharmacology) med an anticoagulant extracted from the mouth glands of leeches
[C20: from Latin hirudin-, hirudo leech + -in]


(ˈhɪr yə dɪn, ˈhɪr ə-, hɪˈrud n)

a polypeptide obtained from the buccal gland of leeches, used in medicine chiefly as an anticoagulant.
[1900–05; formerly trademark]
References in periodicals archive ?
esume therapy after 24 h * Rivaroxaban (Xarelto) Direct thrombin inhibitors (Argotraban, Desirudin) Wait for 4 h after the last dose to do the procedure.
Direct thrombin inhibitors (DTIs), such as argatroban, dabigatran, lepirudin, desirudin, and bivalirudin, which bind to thrombin and block its enzymatic activity, are widely and effectively used in the treatment of thromboembolic diseases; however, dabigatran is not orally available due to its high polarity [7].
Smith, "Impact of stage 3B chronic kidney disease on thrombosis and bleeding outcomes after orthopedic surgery in patients treated with desirudin or enoxaparin: insights from a randomized trial," Journal of Thrombosis and Haemostasis, vol.
The Pediatric Health Information System database was queried for pediatric patients discharged from January 1, 2004 to December 31, 2011 if they received one of the following DUs during admission: argatroban, bivalirudin, desirudin, or lepirudin.