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Related to Desirudin: Lepirudin


 (hîr-o͞od′n, hîr′ə-dən, -yə-)
A substance secreted by the buccal glands of leeches, capable of preventing coagulation by inactivating thrombin and used in medicine as an anticoagulant.

[Originally a trademark, from Latin hirūdō, leech.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Pharmacology) med an anticoagulant extracted from the mouth glands of leeches
[C20: from Latin hirudin-, hirudo leech + -in]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˈhɪr yə dɪn, ˈhɪr ə-, hɪˈrud n)

a polypeptide obtained from the buccal gland of leeches, used in medicine chiefly as an anticoagulant.
[1900–05; formerly trademark]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
References in periodicals archive ?
esume therapy after 24 h * Rivaroxaban (Xarelto) Direct thrombin inhibitors (Argotraban, Desirudin) Wait for 4 h after the last dose to do the procedure.
Direct thrombin inhibitors (DTIs), such as argatroban, dabigatran, lepirudin, desirudin, and bivalirudin, which bind to thrombin and block its enzymatic activity, are widely and effectively used in the treatment of thromboembolic diseases; however, dabigatran is not orally available due to its high polarity [7].
Smith, "Impact of stage 3B chronic kidney disease on thrombosis and bleeding outcomes after orthopedic surgery in patients treated with desirudin or enoxaparin: insights from a randomized trial," Journal of Thrombosis and Haemostasis, vol.
The Pediatric Health Information System database was queried for pediatric patients discharged from January 1, 2004 to December 31, 2011 if they received one of the following DUs during admission: argatroban, bivalirudin, desirudin, or lepirudin.