(redirected from Desmosomal cadherins)
Also found in: Medical, Encyclopedia.


(Biology) cytology a structure in the cell membranes of adjacent cells that binds them together
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˈdɛz məˌsoʊm)

a plaquelike site on a cell surface that functions in maintaining cohesion with an adjacent cell.
[1930–35; < Greek desm(ós) band, chain (see desmid) + -o- + -some3]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
Mentioned in ?
References in periodicals archive ?
Desmosomes form the adhesive core of intercellular junctions, which consist of desmosomal Cadherins, desmogleins (Dsgs), and desmocollins (figure 1).
Desmosomal cadherins. Curr Opin Cell Biol 2002; 14: 537.
Ultrastructural studies show that E-cadherin on the cytoplasmic membrane of the keratinocytes is shifted to desmosomes under physiological conditions and therein expresses an adhesion function in association with other desmosomal cadherins.10 We observed that E-cadherin was strongly expressed membranously in all normal keratinocytes and specialized epithelial structures.
Desmogleins are calcium-binding transmembrane glycoproteins, members of the desmosomal cadherins that provide adhesive integrity to desmosomes between adjoining keratinocytes; They consist of proteins Dsg1, Dsg2, Dsg3, and Dsg4.