Many developmental diseases
have in common the failure of brain cells to mature at the same rate as they do in healthy people.
The latter is called whole exome sequencing, and is a popular and practical investigation tool for developmental diseases
Developmental biology is becoming more focused on disease, and focused on what developmental diseases
can teach us about the functions of molecules, she said.
Though not conscious, the miniature brain, which resembles that of a five-week-old foetus, could potentially be useful for scientists who want to study the progression of developmental diseases
, including Alzheimer's.
Rene Anand, the professor of biological chemistry and pharmacology at the university, has expressed hope that the feat could help scientists studying developmental diseases
and help them understand conditions such as Alzheimer's, Parkinson's, and autism.
For example, numerous developmental diseases
cannot be studied using animal models, nor by isolating cells from patients.
An introductory part on diagnostics is followed by sections concentrating on specific disorders: epilepsy and vertigo, headaches and developmental diseases
, various neuropathies, metabolic and inflammatory disorders, tumors and traumas, muscle and sleep disorders, and others.
The etiology might be of non inflammatory disease conditions which included degenerative joint disease and osteoarthritis, characterised by degeneration of the articular cartilage, hypertrophy of the bone margin and changes in the synovial membrane which might be primary due to aging or secondary due to developmental diseases
These conditions include food hypersensitivities, obesity and eating disorders, inborn errors of metabolism, developmental diseases
, diseases of various body systems, HIV/AIDS, oncology and sickle cell disease, and burns, and enteral nutrition and herbs and phytomedicines.
These diseases include common debilitating diseases such as Alzheimer's disease, Parkinson's disease and other neurodegenerative disorders as well as epilepsies and childhood developmental diseases
including forms of autism and learning disability.
Among the topics are a nephrologist's perspective on renal biopsy, glomerular diseases associated primarily with asymptomatic or gross hematuria, metabolic diseases of the kidney, thrombotic micro-angiopathies, cystic and developmental diseases
, the aging kidney, the pathology of renal transplantation, and tumors of the kidney.
My article on classification of cystic and developmental diseases
in this issue adopts and builds upon many of Dr Bernstein's conceptual constructs, while attempting to serve as a temporary bridge to the future when molecular-based schema will take center stage.