(redirected from Diamine oxidase)
Also found in: Thesaurus, Medical, Encyclopedia, Wikipedia.


 (hĭ-stăm′ə-nās′, -nāz′, hĭs′tə-mə-)
An enzyme that catalyzes the inactivation of histamine and is found in the digestive system.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Biochemistry) an enzyme, occurring in the digestive system, that inactivates histamine by removal of its amino group. Also called: diamine oxidase
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(hɪˈstæm əˌneɪs, -ˌneɪz)

an enzyme that catalyzes the decomposition of histamine, used in treating allergies.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.histaminase - enzyme that acts as a catalyst in converting histidine to histamine
enzyme - any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
A newer supplement product containing an enzyme known as diamine oxidase (DAO) has been shown to give rapid symptom relief for allergic reactions.
However, patients with higher urticaria activity scores at baseline did show a decline in diamine oxidase activity with the diet.
The levels of inflammatory factors tumor necrosis factor (TNF)-[micro], interleukin (IL)-6, IL-1[sz], and diamine oxidase (DAO) measured by enzyme-linked immunosorbent assay were used to evaluate the inflammation reactivity as well as the integrity of small intestine.
Metabolism of histamine is mostly dependent on one-carbon metabolism via histamine N-methyltransferase (H-NMT) and deamination via diamine oxidase (DAO).
Several markers have been studied, including [alpha]-fetoprotein (AFP), fetal fibronectin test (fFN), insulin-like growth factor binding protein-1 (IGFBP-1), prolactin, diamine oxidase activity, [beta]-subunit of human chorionic gonadotropin ([beta]-hCG) and placental [alpha]-microglobulin-1 in order to identify PROM (9,10).
The oxime derivatives of 5-acyl-3-methylsulfanyl-1,2,4- triazine were tested with pea-seedling diamine oxidase as the enzyme is known to be inhibited by oxime compounds.
Inflammation markers (tumor necrosis factor and myeloperoxidase) and indices of intestinal damage (serum diamine oxidase) were increased.
In experiment 1 and 2, the levels of diamine oxidase (DAO) in the serum were analyzed according to a test kit (Nanjing Jiancheng Bioengineering Institute, Nanjing, China), which were expressed as U/L.
1,4-Diamino-2-butyne as the mechanism-based pea diamine oxidase inhibitor.
Copper is absorbed from the small intestine, bound to plasma albumin, and transported to the liver where copper is incorporated into various copper metalloenzymes (cytochrome oxidase, superoxide dismutase, lysine oxidase, dopamine beta-hydroxylase, spermine oxidase, tyrosinase, uricase, benzylamine oxidase, diamine oxidase, and tryptophan 3,3-dioxygenase) and into the plasma protein ceruloplasmin.