A compound called
diosgenin in the vegetable has been linked to enhanced neuron growth, memory and learning abilities, according to (https://www.healthline.com/nutrition/yam-benefits#section4) Healthline.
The major compounds in fenugreek are flavonoids, terpenoids and saponin (
diosgenin).
Development and validation of HPTLC method for simultaneous estimation of
diosgenin and quercetin in fenugreek seeds (Trigonella foenum-graceum).
Antineoplastic and Apoptotic Potential of Traditional Medicines Thymoquinone and
Diosgenin in Squamous Cell Carcinoma.
Total saponin contents were determined by spectrophotometric method using
diosgenin as a standard (Hiai et al., 1976).
The discorine, a type of alkaloid that dissolves in water during the production of steroid
diosgenin, was found to be effective in the release of fish breeding hormones.
Ji et al., in their study entitled "
Diosgenin, a Novel Aldose Reductase Inhibitor, Attenuates the Galactosemic Cataract in Rats," investigated the potentially protective role of
diosgenin, an aldose reductase inhibitor (ARI), against the development of sugar cataract in rats.
Byun et al., "
Diosgenin inhibits macrophage-derived inflammatory mediators through downregulation of CK2, JNK, NF-[kappa]B and AP-1 activation," International Journal of Immunopharmacology, vol.
Chadha, "
Diosgenin and beta-sitosterol: isolation from solanum xanthocarpum tissue cultures," Science, vol.
Tohda, "
Diosgenin restores A[beta]-induced axonal degeneration by reducing the expression of heat shock cognate 70 (HSC70)," Scientific Reports, vol.
Diosgenin, asteroid saponins of Trigonella foenum graecum (fenugreek), inhibits azoxymethane-induced aberrant crypt foic formation in F344 rats and induces apoptosis in HT-29 human colon cancer cells.
Hence, they proved that
diosgenin was the main effective saponin on inhibiting liver X receptor-alpha and SREBP-1c levels in HepG2 cells.