Down syndrome


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Down syndrome

 (doun) or Down's syndrome (dounz)
n.
A congenital disorder caused by the presence of an extra 21st chromosome and marked usually by moderate to severe intellectual disabilities, short stature, and a flattened facial profile. Also called trisomy 21.

[After John Langdon Haydon Down (1828-1896), British physician.]

Down′

(or Down's′) syn′drome


n.
a genetic disorder associated with the presence of an extra chromosome 21, characterized by mental retardation, weak muscle tone, and epicanthic folds at the eyelids.
Formerly, mongolism. Also called trisomy 21.
[1960–65; after John Latin. H. Down (1828–96), British physician]

Down syndrome

A congenital disorder caused by the presence of an extra 21st chromosome. People with Down syndrome have mild to moderate mental retardation, short stature, and a flattened facial profile.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.Down syndrome - a congenital disorder caused by having an extra 21st chromosomeDown syndrome - a congenital disorder caused by having an extra 21st chromosome; results in a flat face and short stature and mental retardation
trisomy - chrosomal abnormality in which there is one more than the normal number of chromosomes in a cell
Translations
síndrome de Down
Downin oireyhtymäDownin syndroomamongolismimongoloidismi
syndrome de Down
sindrom Down
ダウン症
downsyndroommongolismesyndroom van Down
Downs syndrom

Down syn·drome

[MIM*190685]
n. síndrome de Down, anormalidad citogenética del cromosoma 21 caracterizada por retraso mental y facciones mongoloides.
References in periodicals archive ?
Persons with Down syndrome often manifest a variety of immune defects and several risk factors for adverse outcomes for pandemic (H1N1) 2009, including obesity, diabetes, and cardiovascular diseases.
Among them are dosage imbalance effects at transcription and proteome levels in the gene expression in Down Syndrome, a neuropsychological perspective on social functioning, whether the dysfunctional gastro-intestinal tract in Down's Syndrome is congenital or acquired, informed choice in prenatal screening, Down's Syndrome and dysphagia, machine learning applied to second-trimester Down's Syndrome screening, the influence of oromotor function and diet consistency on caries experience and growth rate in cerebral palsied individuals, the dental evidence for prenatal and early postnatal growth insults in Down syndrome, and a new look at pathogenesis in Alzheimer's Disease dementia from the perspective of Down's Syndrome.
Conventional wisdom among scientists for years has suggested that, because individuals with Down syndrome have an extra chromosome, the disorder most likely results from the presence of too many genes or proteins contained in that additional structure.
Sarah Palin of Alaska was introduced to America as John McCain's running mate, she, in turn, was introducing America to a person not seen much in America anymore, a baby with Down syndrome.
Now published in a newly revised and updated edition, "Babies with Down Syndrome: A New Parents' Guide" is a guide focused on giving new parents everything they need to deal with their child who has been afflicted with Down Syndrome.
People with Down syndrome are at least 10 times as likely as people without it to develop leukemia.
CHILDREN from a Liverpool Down syndrome support group got to meet Father Christmas at their annual party.
The Arc of Whatcom County's Down syndrome Outreach program will host the fourth annual Buddy Walk of Whatcom County Oct.
NEW RECOMMENDATIONS from the Society of Obstetricians and Gynaecologists of Canada (SOGC) discriminate against citizens with Down syndrome, says the Canadian Down Syndrome Society (CDSS).
We present a case referred to our clinic with a lower respiratory tract infection and later diagnosed as Down syndrome with concurrent Fallot pentalogy.
Bauer, mother of a child with Down syndrome, underscored one aspect of that hypocrisy in an October 22 syndicated column.
Who says that with a little help - maybe an older buddy to hold their hand - a child with Down Syndrome couldn't be out there on that youth soccer field kicking the ball around and having fun?

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