doxorubicin

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dox·o·ru·bi·cin

(dŏk′sə-ro͞o′bĭ-sĭn)
n.
An antibiotic, C27H29NO11, obtained from the bacterium Streptomyces peuceticus and used as an anticancer drug.

[Alteration of (hy)d(r)oxy + rubi(domy)cin, antibiotic from which it is derived (Latin rubidus, red, from its red crystals; see rubidium + -mycin).]

doxorubicin

(ˌdɒksəˈruːbəsɪn)
n
an antineoplastic antibiotic used in the treatment of cancer
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.doxorubicin - an antibiotic used as an anticancer drug
antibiotic, antibiotic drug - a chemical substance derivable from a mold or bacterium that can kill microorganisms and cure bacterial infections; "when antibiotics were first discovered they were called wonder drugs"
Translations

doxorubicin

n doxorubicina
References in periodicals archive ?
Additionally, Arcus Biosciences initiated a Phase 1/1b study, in collaboration with Infinity, evaluating IPI-549 in a novel combination regimen with AB298, Arcus's dual adenosine receptor antagonist, and Doxil, a chemotherapy, in patients with advanced TNBC.
Arcus Biosciences Collaboration Study Initiating in Q3: This Phase 1 trial, to be conducted by Arcus, will evaluate a checkpoint-inhibitor free, novel triple-combination regimen of IPI-549 + AB928 (dual adenosine receptor antagonist) + Doxil in advanced TNBC patients.
Drug Brand Names Carbamazepine * Carbatrol, Gemcitabine injection Tegretol * Gemzar Carboplatin * Paraplatin Lithium * Eskalith, Lithobid Divalproex sodium * Olanzapine * Zyprexa Depakote Paditaxel injection Doxorubicin liposome * Abraxane injection * Doxil Quetiapine * Seroquel Bottom Line
He has had significant involvement in the development and/or global registration of many drugs including Krystexxa, Onivyde, Oncaspar, Velcade, Alimta, DOXIL and Accolate.
To date, there are several FDA approved NPs such as Doxil (1995), Feridex (1996), Mylotarg (2000), Zevalin (2002), Abraxane (2005, 2013), Oncospar (2006), and Ontac (2008) that utilize EPR effect to accumulate in solid tumors [23].
Kramer, "Phase II evaluation of liposomal doxorubicin (Doxil) in recurrent or advanced leiomyosarcoma of the uterus: a Gynecologic Oncology Group study," Gynecologic Oncology, vol.
These data include results from pooled analyses of three Phase one expansion cohorts and from a Phase 1b/2 study, FORWARD II, assessing mirvetuximab soravtansine in combination with Avastin (bevacizumab), carboplatin, Doxil (pegylated liposomal doxorubicin), or Keytruda (pembrolizumab).
For example, the Food and Drug Administration (FDA) has permitted clinical trials for at least two novel nanoparticle based formulations with incorporated antitumor drugs, for example, Doxil (Janssen Biotech, Horsham, PA, USA) and Nab-paclitaxel (Abraxane).
Name Nanocarrier Characteristics Doxil PEGylated liposome/ Inhibits nucleic doxorubicin acid synthesis, ROS hydrochloride Abraxane Nanoparticle Microtubule albumin-bound stabilizing paclitaxel Carbon CNTs, nanographene DNA damage by ROS, nanomaterials oxide peroxidation (carbon nanotubes (CNTs), graphene oxide) Gold Au NPs (spheres, DNA damage by ROS, nanoparticles rods, and shells), mitochondrial Au NPs modified with dysfunction.
Sun Pharma's top selling drugs are Absorica, Gleevec and Doxil, while for Dr.