Duchenne muscular dystrophy

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Du·chenne muscular dystrophy

A severe form of muscular dystrophy that begins in early childhood and almost exclusively affects males, characterized by progressive weakening of the muscles and usually leading to death from respiratory or cardiac failure. It is caused by lack of the protein dystrophin in muscle cells as a result of a recessive genetic mutation on the X chromosome.

[After Guillaume B.A. Duchenne (1806-1875), French physician.]
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