dynorphin

(redirected from Dynorphins)
Also found in: Medical.

dynorphin

(daɪˈnɔːfɪn) med
n
1. (Medicine)
a. an opioid peptide produced in the brain, used as a form of pain relief and in the treatment of cocaine addiction
b. (as modifier): dynorphin blockers.
2. (Medicine) (as modifier): dynorphin blockers.
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
References in periodicals archive ?
Electroacupuncture at low frequencies mainly releases enkephalins and endorphins and at high frequencies, primarily dynorphins. (17)
[2] Other placental hormones include corticotropin-releasing hormone, endorphins, dynorphins, gonadotropin-releasing hormones, inhibin, leptin, prolactin, and prorenin.
Other endogenous opioids include endorphin, formed after the cleavage of the precursor proopiomelanocortin (POMC) protein, and dynorphins derived from cleavage of prodynorphin.
And the dynorphins interact selectively with the kappa opioid receptor (Gianoulakis, 1993).
Opioid receptors are activated by peptide neurotransmitters (endorphins, dynorphins and enkephalins) in the brain and also by plant-derived and synthetic drugs mimicking these peptides: among them morphine, codeine, oxycodone and heroin.
Opioid peptides include the endorphins, enkephalins, and dynorphins. Enkephalins are frequently found in presynaptic (axoaxonic) synapses.
There are endogenous opioids including endorphins, endomorphins, enkephalins, dynorphins, and nociceptin.
Opioid receptors can be found within the central nervous system (CNS) as well as throughout the peripheral tissues, and they are normally stimulated by endogenous peptides (endorphins, enkephalins, and dynorphins) produced in response to noxious stimulation.
Dynorphins are opioid peptides that derive from the prodynorphin precursor and are the presumed endogenous ligands for the [kappa] opioid receptor (Chavkin et al., 1982).
The topics include neuropeptide biosynthesis, dynorphins in central nervous system pathology, the influence of anabolic androgenic steroids on dynorphinergic pathways in the rat's brain, angiotensin II receptors and neuroprotection, and classic and nonclassic cases of interactions between opioid ligands and their receptors.
Biogenesis, release and interaction of enkephalins and dynorphins. Brit Med Bull 1983; 39:17-24.
Dynorphins are a class of endogenous opioids that interact with the -opioid receptor and are thought to mediate negative emotional states.