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Related to Elmiron: interstitial cystitis


Any of a group of polysaccharides found with cellulose in many woody plants and yielding pentoses on hydrolysis.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Biochemistry) biochem any of a group of polysaccharides, having the general formula (C5H8O4)n: occur in plants, humus, etc
[C20: from pentose + -an]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˈpɛn təˌsæn)

any of a class of polysaccharides that occur in plants, humus, etc., and form pentoses upon hydrolysis.
[< German (1892), =Pentos(e) pentose + -an -ane]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
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Pentosan (Elmiron), a heparinlike compound, is an oral drug that is indicated for the relief of bladder pain or discomfort associated with interstitial cystitis.
The sole medication approved by the Food and Drug Administration for IC is pentosan polysulfate sodium (Elmiron), and it should be reserved for the minority of patients who don't experience significant improvement after giving the diet a reasonable shot, Dr.
In this article, we review the AUA diagnostic and treatment algorithms and the results of recently published randomized trials comparing the efficacy of various treatment modalities for IC/BPS, including pentosoan polysulfate sodium (PPS; Elmiron, lanssen Pharmaceuticals, Titusville, New Jersey) and botulinum toxin (Botox, Allergan, Irvine, California) with hydrodistension.
* Elmiron (pentosan polysulfate sodium) is an oral drug approved to treat interstitial cystitis.
Under the impression of IC, she was treated with antispasmodics, digestive medicines, alpha1-blocker and pentosan sulfuric polyester (Elmiron, Alza Pharmaceuticals, Mountain View, CA), and her symptoms improved.
Shoskes notes that a small subset of these patients with bladder-specific symptoms may require drugs such as amitriptyline (Elavil) and pentosan (Elmiron) or neuromodulation, using an implantable device that regulates nerves controlling the bladder.
Elmiron (the only FDA-approved oral medication to treat IC currently on the market) had one of the best outcomes.
The only drug specifically approved for IC is pentosan (Elmiron).
The newly diagnosed interstitial cystitis patient is usually offered multimodality-specific therapy in the form of agents such as pentosan poly-sulfate sodium (Elmiron) to restore the protective mucosal glycosaminoglycans layer of the bladder, tricyclic antidepressants such as amitriptyline (Elavil) to reduce pain and relax the bladder, and antihistamines--especially hydroxyzine (Atarax and Vistaril)--to suppress histamine release from bladder wall mast cells.
In clinical studies, Elmiron (pentosan polysulfate sodium) improved symptoms in 38 percent of people who used it.