enalapril

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e·nal·a·pril

 (ĭ-năl′ə-prĭl)
n.
An ACE inhibitor drug, C20H28N2O5, used in its maleate form to treat hypertension.

[(ph)en(yl)ala(nine) + (capto)pril.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

enalapril

(ɪˈnæləˌprɪl)
n
(Pharmacology) an ACE inhibitor used to treat high blood pressure and congestive heart failure
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.enalapril - an ACE inhibitor (trade name Vasotec) that blocks the formation of angiotensin in the kidney and so results in vasodilation; administered after heart attacks
ACE inhibitor, angiotensin-converting enzyme inhibitor - an antihypertensive drug that blocks the formation of angiotensin II in the kidney, leading to relaxation of the arteries; promotes the excretion of salt and water by inhibiting the activity of the angiotensin converting enzyme; also used to treat congestive heart failure
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Translations

enalapril

n enalapril m
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
Enalapril and Enalaprilat. Enalapril maleate is chemically described as [(S)-1-(N-(1-(ethoxycarbonyl)-3-phenylpropyl)-L-alanyl)-Lproline (Z)-2-butenedioate salt], and its empirical formula is ([C.sub.20][H.sub.28][N.sub.2][O.sub.5] - [C.sub.4][H.sub.4][O.sub.4]) (Figure 1(a)).
Furthermore, the addition of enalaprilat dihydrate and valsartan, an Ang II receptor antagonist, significantly upregulated miR-145 expression under HG stimulation [20].
In acute heart failure use intravenous Nitroglycerin and intravenous Enalaprilat. Give vasodilators (besides diuretics) when SBP is 140 mm Hg (28).
Liquid chromatography-tandem mass spectrometry (LC-MS) method for the assignment of enalapril and enalaprilat in human plasma.
The AHA/ASA guidelines list the following antihypertensive regimens as treatment options before alteplase: labetalol 10-20 mg IV over 1-2 minutes, nicardipine 5 mg/h infusion titrated to desired blood pressure, or other agents (e.g., hydralazine, enalaprilat) when appropriate.
demonstrated improved FMD acutely in response to quinaprilat but not to increasing doses of enalaprilat in patients with heart failure.
A similar study demonstrated this correspondence in the case of ramiprilat [4], enalaprilat [5], and perindopril [39] in different solvents.
This compound, Fosinoprilat, was more potent than captopril but less potent than enalaprilat. Fosinoprilat proved to have the same problem as enalaprilat and other carboxylate-containing ACE inhibitors like poor bioavailability.
Work in children with bidirectional cavopulmonary shunts demonstrated that enalaprilat did not increase total cardiac output but redistributed flow to the lower body, with a concomitant decrease in arterial oxygen saturation (25).
Reduced levels of Ang II (via enalaprilat) caused levels of Ang-(1-7) to decrease.