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Related to Endocardial cushions: endocardial cushion defect


n. pl. en·do·car·di·a (-dē-ə)
The thin serous membrane, composed of endothelial tissue, that lines the interior of the heart.

[New Latin : endo- + Greek kardiā, heart; see kerd- in Indo-European roots.]

en′do·car′di·al adj.


(ˌɛndəʊˈkɑːdɪəl) or


1. (Anatomy) of or relating to the endocardium
2. (Anatomy) within the heart


(ˌɛn doʊˈkɑr di əl)

1. situated within the heart.
2. Also, en•do•car•di•ac (ˌɛn doʊˈkɑr diˌæk) of or pertaining to the endocardium.
[1840–50; endo- + Greek kardí(a) heart + -al1; or endocardi (um) + -al1]
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DISCUSSION: The characteristic heart defects in Down syndrome derives from the abnormal development of endocardial cushions and results in a spectrum of defects involving the atrioventricular septum and valves.
0 cm CVRL foetal heart, the two conspicuous masses of loosely organized mesenchymal tissue called endocardial cushions developed (Figure 3) in dorsal and ventral wall of atrioventricular canal.
As cardiac morphogenesis proceeds through stage HH 21, valvulogenesis and septation begins and thus, an epithelial--mesenchymal transition occurs within the endocardial cushions of the atrioventricular region and the outflow tract.