islets of Langerhans

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is·lets of Lang·er·hans

 (ī′lĭts; läng′ər-häns′)
pl.n.
Irregular clusters of endocrine cells scattered throughout the tissue of the pancreas that secrete insulin and glucagon. Also called islands of Langerhans.

[After Paul Langerhans (1847-1888), German pathologist.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

islets of Langerhans

(ˈlæŋəˌhæns) or

islands of Langerhans

pl n
(Anatomy) small groups of endocrine cells in the pancreas that secrete the hormones insulin and glucagon
[C19: named after Paul Langerhans (1847–88), German physician]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

is·lets of Lang·er·hans

(ī′lĭts əv läng′ər-häns′)
Irregular clusters of endocrine cells that are scattered throughout the tissue of the pancreas and secrete insulin.
The American Heritage® Student Science Dictionary, Second Edition. Copyright © 2014 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.islets of Langerhans - cell clusters in the pancreas that form the endocrine part of that organ; secrete insulin and other hormones
ductless gland, endocrine gland, endocrine - any of the glands of the endocrine system that secrete hormones directly into the bloodstream
pancreas - a large elongated exocrine gland located behind the stomach; secretes pancreatic juice and insulin
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
(5) Both exocrine and endocrine pancreas cells have diseases which affect the pancreas.
While diabetes is primarily understood as a disease of the endocrine pancreas, other endocrine glands including adipose tissue, gastrointestinal endocrine system, pituitary, parathyroid, thyroid, adrenals and gonads are associated with diabetes in multiple ways, in both the etiopathogenesis of diabetes and development of comorbid states.
PTF1A is a transcription factor that is required for the formation of the exocrine pancreas and the correct spatial organization of the endocrine pancreas in mice (23).
Klersy et al., "TNM staging of neoplasms of the endocrine pancreas: results from a large international cohort study," Journal of the National Cancer Institute, vol.
The usefulness of continuous glucose monitoring during insulinoma resection using an artificial endocrine pancreas has been reported [14].
This latter result could be explained by another study [49], in which higher gene and protein expressions of D3, an enzyme that degrades T3, were observed in the endocrine pancreas of mice at E17.5.
We analyzed whether the islet function modifications induced by DJB surgery in HyO rats were due to alterations in endocrine pancreas morphology.
The endocrine system includes the hypothalamic--pituitary--adrenal axis, the hypothalamic--pituitary--gonadal axis, the hypothalamic--pituitary--thyroid axis, the hypothalamic--pituitary--growth hormone/insulin-like growth factor-1 axis, and the hypothalamic--posterior pituitary axis, as well as other sources of hormones, such as the endocrine pancreas and endocrine adipose tissue.
Conclusion: Sodium cyclamate affects the histomorphology of endocrine pancreas by increasing the area of islets of langerhans in treated group.
The study, conducted by scientists at the University of California, San Francisco (UCSF) and ViaCyte, documented in a mouse model that a selective blockade of specific elements of the immune system, co-stimulatory blocking agents CTLA4Ig and anti-CD154, allows the implanted precursor cells to avoid immune rejection and develop into the insulin-producing and other cells of the healthy endocrine pancreas. These cells release pancreatic endocrine hormones such as insulin in response to changes in blood sugar.