According to these results bromination selectivity occurred at a-carbon of the ketone favorable to enolization
It starts with enolization
of glucose 76 to form 1,2-dienol 77.
The observed results were quantified using NMR spectroscopy with an internal standard leading to a general process that could potentially negate the need for the traditional three step process of oxidation, enolization
, and 0-alkylation.
1] due to vNH and vC=O groups respectively, which disappears in the corresponding complexes suggesting the enolization
of the -C=O of the aroyl keto group giving rise to the -C=N-N=C moiety [15 ] and consequent deprotonation upon coordination.
ability of the carbonyl group is well known.
Our interest in enolizable ketones resulted in a recent paper reporting on the syntheses and enolization
of 4-alkyl-2-(2-pyridyl) cyclohexanones (Sund et al.
The reaction mixture was stirred for further 45 minutes to ensure the complete enolization
It has been reported in the literature that in alkaline medium sugar will form enediol with the hydroxyl group and also that the rate of enolization
is the same as the rate of oxidation  However, in the present study, the double reciprocal plots of the pseudo-first-order rate constants against the sugar concentrations were linear (fig.
The formation of possible kinetic enolization
products (4-oxygenated products) was not observed.