ethionamide


Also found in: Medical, Wikipedia.
Related to ethionamide: isoniazid, Pyrazinamide, cycloserine, ethambutol

ethionamide

(ˌiːθɪˈɒnəˌmaɪd)
n
(Medicine) med an antibiotic used in treating tuberculosis
Translations

ethionamide

n etionamida
References in periodicals archive ?
Therapy was reinitiated with RIF, INH, ethionamide (ETA) and pyrazinamide (PZA).
For patient 1, additional resistance to ethionamide and linezolid was detected in a drug susceptibility test in the final phase.
PZA, like Isoniazid and Ethionamide, is a pro drug which must be converted into its active form, Pyrazinoic acid.
The pyridine nucleus is also a constituent of many structurally simple drugs such as ethionamide and isoniazid, both these drugs are important prodrugs for enoyl-acyl carrier protein reductase used in the treatment of tuberculosis, bupicomide used as dopamine, b-hydroxylase inhibitor in the treatment of hypertension and amrinone used as phosphodiesterase 3 inhibitor in the treatment of heart failure (Fig.
The therapy was empirically optimized by adding ethionamide, extending the period of streptomycin and increasing the local support for directly observed treatment, while the results of phenotypic testing from isolate 3 were still pending.
Medications Side effects Isoniazid Category C: possible increased risk of hepatitis/peripheral neuropathy Rifampin Category C: rare cases of fetal abnormalities and hemorrhagic disease Ethambutol Category B Pyrazinamide Category C: detail teratogenicity data are not available Fluoroquinolones Category C: causes arthropathies Ethionamide Category C: teratogenic in laboratory animals Para-aminosalicylic acid Category C: adverse effects are not certain Cycloserine Category C: adverse effects are not certain Streptomycin Category D: congenital deafness Kanamycin/amikacin Category D: similar side effect with streptomycin Table 4: Control of transmission of TB in pregnancy [4].
Predisposing Drugs Antituberculosis agents: Isoniazid Pyrazinamide Antiepileptic drugs: Hydantoins Ethionamide Phenobarbital Diazepam Chemotherapy and immunosuppressive drugs 6-Mercaptopurine 5-Fluorouracil Chlorambucil Azathioprine Chloramphenicol
Hepatitis caused by rifampin is usually associated with ethionamide use.
For TB, they include capreomycin, kanamycin, amikacin, ethionamide, para-aminosalicylic acid, cycloserine, ciprofloxacin, ofloxacin, levofloxacin, clofazimine, and the new medicines bedaquiline and delamanid.