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Related to Exons: RNA splicing


A nucleotide sequence that is found in a gene, codes information for protein synthesis, and is transcribed to messenger RNA.

[ex(pressed) + -on.]

ex·on′ic adj.


(Historical Terms) Brit one of the four officers who command the Yeomen of the Guard
[C17: a pronunciation spelling of French exempt exempt]


(Genetics) any segment of a discontinuous gene the segments of which are separated by introns. Compare intron
[C20: from ex-1 + -on]
exˈonic adj


(ˈɛk sɒn)

a segment of DNA that is transcribed to RNA and specifies the sequence of a portion of protein.
[1975–80; ex(pressed sequence) + -on1]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.exon - sequence of a gene's DNA that transcribes into protein structures; "exons are interspersed with introns"
deoxyribonucleic acid, desoxyribonucleic acid, DNA - (biochemistry) a long linear polymer found in the nucleus of a cell and formed from nucleotides and shaped like a double helix; associated with the transmission of genetic information; "DNA is the king of molecules"
intron, noncoding DNA - sequence of a eukaryotic gene's DNA that is not translated into a protein
References in periodicals archive ?
Several mutations have been confirmed to be related to the prognosis of GIST, including KIT mutations in exons 9, 11, 13, and 17 and PDGFRA mutations in exons 12, 14, and 18 [26].
In the TK domain of EGFR, activating somatic mutations from exons 18 to 21 were first found in patients with lung adenocarcinoma in 2004 (6).
Mutation screening of all exons and exon-intron boundaries was performed by Sanger sequencing, and mini haplotype analysis was carried out by genotyping of Short Tandem Repeat (STR) and Variable Number Tandem Repeat (VNTR) alleles.
The most common mutations are found in exons 3, 4 of this gene.
The BDNF gene has a complicated structure with eight 5' noncoding exons (I-IXa), each of which can splice to a common coding exon (IX) to form a functional transcript.
The mutational analysis of exons 18-21 of EGFR gene was performed using nested polymerase chain reaction- (PCR-) based direct sequencing.
Various machine learning approaches are used in cassette exons identification [13-16].
The main cause of the disease is attributed to mutations in one of the largest protein-coding genes in the human genome called dystrophin that spans 79 exons (2.2 megabases) and stabilizes muscle cells by anchoring the cytoskeleton to the extracellular matrix with other proteins, in a complex known as the dystrophin-associated glycoprotein complex (DAGC) [18].
LHCGR is located on chromosome 2p21 and contains 12 exons. The LHCGR gene encodes a 699 amino acid protein that consists of an N-terminal cysteine-rich region, a tandem leucine-rich repeats (LRRs) region and a C-terminal cysteine-rich region (2,3).
Polymorphisms of the GnRHR gene in giant panda: Comparative analysis of the giant panda GnRHR gene sequencing indicated two single mutation sites that were found in exons 1 and 2, respectively.
KCNE3 has three exons. The length of KCNE3-exon-1 was 462 bp, and the sense primer (5'-3') was AGGCTTTCGGTCTGGTC, whereas the antisense primer (5'-3') was GGTTCCACAGTCTCACGGAG.