exonuclease

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ex·o·nu·cle·ase

 (ĕk′sō-no͞o′klē-ās′, -āz′, -nyo͞o′-)
n.
Any of a group of enzymes that catalyze the hydrolysis of single nucleotides from the end of a DNA or RNA chain.

exonuclease

(ˌɛksəʊˈnjuːklɪˌeɪz)
n
(Biochemistry) an enzyme that is capable of detaching the terminal nucleotide from a nucleic acid chain. Compare endonuclease
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.exonuclease - a nuclease that releases one nucleotide at a time (serially) beginning at one of a nucleic acid
nuclease - general term for enzymes that catalyze the hydrolysis of nucleic acid by cleaving chains of nucleotides into smaller units
References in periodicals archive ?
The first generation BNA (2',4'-BNA/LNA) has good RNA binding affinity and fair stability to exonucleases.
Although there is strong evidence suggesting that free DNA, in sediments surviving degradation and metabolism by bacterial and fungal exonucleases, will quickly bind to clay, sand, humic substances and organomineral complexes in the sediment (Crecchio & Stotzky 1998), DNA leaching has proved a problem under certain settings.
To avoid degradation by exonucleases, ODNs were protected by incorporating nuclease resistant phosphorothioate bonds in the last nucleotides at the 5'- and 3'-ends, respectively.