exonuclease

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ex·o·nu·cle·ase

 (ĕk′sō-no͞o′klē-ās′, -āz′, -nyo͞o′-)
n.
Any of a group of enzymes that catalyze the hydrolysis of single nucleotides from the end of a DNA or RNA chain.

exonuclease

(ˌɛksəʊˈnjuːklɪˌeɪz)
n
(Biochemistry) an enzyme that is capable of detaching the terminal nucleotide from a nucleic acid chain. Compare endonuclease
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.exonuclease - a nuclease that releases one nucleotide at a time (serially) beginning at one of a nucleic acid
nuclease - general term for enzymes that catalyze the hydrolysis of nucleic acid by cleaving chains of nucleotides into smaller units
References in periodicals archive ?
In addition, chemically modified sgRNA may aid in editing challenging targets even in common cell lines, and can provide protection against exonucleases in prokaryotic cells.
Remaining bound to the DNA molecule until complete removal of the phosphorylated strand is another advantage of this enzyme in comparison to other exonucleases (32).
Chemical modification to the backbone of the double-stranded RNA is carried out to enhance resistance to enzymatic degradations by enzymes such as endonucleases and exonucleases, present in biological fluids such as serum.
The first generation BNA (2',4'-BNA/LNA) has good RNA binding affinity and fair stability to exonucleases.